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ECOLI:ARFB

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) arfB (synonyms: yaeJ)
Protein Name(s) Peptidyl-tRNA hydrolase ArfB

PTH Alternative ribosome-rescue factor B

External Links
UniProt P40711
EMBL L38619
D49445
U70214
U00096
AP009048
U18345
PIR G64743
RefSeq NP_414733.1
YP_488494.1
PDB 2RTX
4DH9
PDBsum 2RTX
4DH9
ProteinModelPortal P40711
SMR P40711
IntAct P40711
STRING 511145.b0191
PaxDb P40711
PRIDE P40711
EnsemblBacteria AAC73302
BAA77867
GeneID 12934377
946046
KEGG ecj:Y75_p0188
eco:b0191
PATRIC 32115495
EchoBASE EB2258
EcoGene EG12354
eggNOG COG1186
HOGENOM HOG000244440
InParanoid P40711
KO K15034
OMA RITQEGV
OrthoDB EOG628F97
PhylomeDB P40711
BioCyc EcoCyc:EG12354-MONOMER
ECOL316407:JW0187-MONOMER
MetaCyc:EG12354-MONOMER
RETL1328306-WGS:GSTH-38-MONOMER
PRO PR:P40711
Proteomes UP000000318
UP000000625
Genevestigator P40711
GO GO:0005737
GO:0004045
GO:0043022
GO:0003747
GO:0072344
InterPro IPR000352
Pfam PF00472
PROSITE PS00745

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0072344

rescue of stalled ribosome

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12354
PANTHER:PTN000117725

P

Seeded From UniProt

complete

enables

GO:0043022

ribosome binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12354
PANTHER:PTN000117725

F

Seeded From UniProt

complete

enables

GO:0004045

aminoacyl-tRNA hydrolase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12354
PANTHER:PTN000117725

F

Seeded From UniProt

complete

involved_in

GO:0072344

rescue of stalled ribosome

PMID:21418110[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0072344

rescue of stalled ribosome

PMID:21051357[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0043022

ribosome binding

PMID:21418110[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004045

aminoacyl-tRNA hydrolase activity

PMID:21418110[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004045

aminoacyl-tRNA hydrolase activity

PMID:21051357[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003747

translation release factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000352

F

Seeded From UniProt

complete

involved_in

GO:0006415

translational termination

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000352

P

Seeded From UniProt

complete

enables

GO:0004045

aminoacyl-tRNA hydrolase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.1.29

F

Seeded From UniProt

complete

involved_in

GO:0006417

regulation of translation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0810

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 Chadani, Y et al. (2011) Escherichia coli YaeJ protein mediates a novel ribosome-rescue pathway distinct from SsrA- and ArfA-mediated pathways. Mol. Microbiol. 80 772-85 PubMed GONUTS page
  3. 3.0 3.1 Handa, Y et al. (2011) YaeJ is a novel ribosome-associated protein in Escherichia coli that can hydrolyze peptidyl-tRNA on stalled ribosomes. Nucleic Acids Res. 39 1739-48 PubMed GONUTS page