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ECOLI:AK1H
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | thrA (synonyms: thrA1, thrA2) | |
| Protein Name(s) | Bifunctional aspartokinase/homoserine dehydrogenase 1
Aspartokinase I/homoserine dehydrogenase I AKI-HDI Aspartokinase Homoserine dehydrogenase | |
| External Links | ||
| UniProt | P00561 | |
| EMBL | V00361 J01706 U14003 U00096 AP009048 V00360 X68872 M28570 M10644 | |
| PIR | B64720 | |
| RefSeq | NP_414543.1 YP_488308.1 | |
| ProteinModelPortal | P00561 | |
| SMR | P00561 | |
| DIP | DIP-2907N | |
| IntAct | P00561 | |
| MINT | MINT-1288804 | |
| STRING | 511145.b0002 | |
| BindingDB | P00561 | |
| PaxDb | P00561 | |
| PRIDE | P00561 | |
| EnsemblBacteria | AAC73113 BAB96579 | |
| GeneID | 12932939 945803 | |
| KEGG | ecj:Y75_p0002 eco:b0002 | |
| PATRIC | 32115099 | |
| EchoBASE | EB0991 | |
| EcoGene | EG10998 | |
| eggNOG | COG0527 | |
| HOGENOM | HOG000271593 | |
| InParanoid | P00561 | |
| KO | K12524 | |
| OMA | QAYDESS | |
| OrthoDB | EOG6M0T34 | |
| PhylomeDB | P00561 | |
| BioCyc | EcoCyc:ASPKINIHOMOSERDEHYDROGI-MONOMER ECOL316407:JW0001-MONOMER MetaCyc:ASPKINIHOMOSERDEHYDROGI-MONOMER | |
| SABIO-RK | P00561 | |
| UniPathway | UPA00034 UPA00050 UPA00050 UPA00051 UPA00051 | |
| PRO | PR:P00561 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P00561 | |
| GO | GO:0016597 GO:0004072 GO:0005524 GO:0004412 GO:0050661 GO:0009090 GO:0009089 GO:0009088 | |
| Gene3D | 3.40.1160.10 3.40.50.720 | |
| InterPro | IPR002912 IPR001048 IPR005106 IPR001341 IPR018042 IPR011147 IPR027795 IPR001342 IPR019811 IPR016040 | |
| Pfam | PF00696 PF01842 PF13840 PF00742 PF03447 | |
| PIRSF | PIRSF000727 | |
| SUPFAM | SSF53633 | |
| TIGRFAMs | TIGR00657 | |
| PROSITE | PS51671 PS00324 PS01042 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0009090 |
homoserine biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10998 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004412 |
homoserine dehydrogenase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10998 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004072 |
aspartate kinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10998 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009090 |
homoserine biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009089 |
lysine biosynthetic process via diaminopimelate |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004412 |
homoserine dehydrogenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004072 |
aspartate kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004072 |
aspartate kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004412 |
homoserine dehydrogenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006520 |
cellular amino acid metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008652 |
cellular amino acid biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009067 |
aspartate family amino acid biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050661 |
NADP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001342 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004072 |
aspartate kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004412 |
homoserine dehydrogenase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008652 |
cellular amino acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009088 |
threonine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0791 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008152 |
metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009089 |
lysine biosynthetic process via diaminopimelate |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00034 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Chassagnole, C et al. (2001) An integrated study of threonine-pathway enzyme kinetics in Escherichia coli. Biochem. J. 356 415-23 PubMed GONUTS page
