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ECOLI:AES

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) aes (synonyms: ybaC)
Protein Name(s) Acetyl esterase

EcE

External Links
UniProt P23872
EMBL D90259
U82664
U00096
AP009048
D00798
L35149
PIR C64778
RefSeq NP_415009.1
YP_488767.1
PDB 4KRX
4KRY
PDBsum 4KRX
4KRY
ProteinModelPortal P23872
SMR P23872
DIP DIP-9062N
IntAct P23872
STRING 511145.b0476
DNASU 947514
EnsemblBacteria AAC73578
BAE76255
GeneID 12934170
947514
KEGG ecj:Y75_p0463
eco:b0476
PATRIC 32116109
EchoBASE EB1093
EcoGene EG11101
eggNOG COG0657
HOGENOM HOG000117644
InParanoid P23872
KO K01066
OMA HIFYIST
OrthoDB EOG6SZ1F1
PhylomeDB P23872
BioCyc EcoCyc:EG11101-MONOMER
ECOL316407:JW0465-MONOMER
MetaCyc:EG11101-MONOMER
SABIO-RK P23872
PRO PR:P23872
Proteomes UP000000318
UP000000625
Genevestigator P23872
GO GO:0005737
GO:0008126
GO:0016787
GO:0034338
GO:0051346
GO:0043433
Gene3D 3.40.50.1820
HAMAP MF_01958
InterPro IPR029058
IPR013094
IPR023508
IPR002168
Pfam PF07859
SUPFAM SSF53474
PROSITE PS01173
PS01174

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0016787

hydrolase activity

PMID:9576853[1]

ECO:0000314

F

Hydrolysis of the substrate by the enzyme. Table 1 and 2

complete

enables

GO:0034338

short-chain carboxylesterase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11101
PANTHER:PTN000546472
UniProtKB:P9WK87

F

Seeded From UniProt

complete

enables

GO:0034338

short-chain carboxylesterase activity

PMID:9576853[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

PMID:9576853[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:9576853[1]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0051346

negative regulation of hydrolase activity

PMID:12374803[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043433

negative regulation of DNA-binding transcription factor activity

PMID:11867639[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008126

acetylesterase activity

PMID:9576853[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023508

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002168
InterPro:IPR013094

F

Seeded From UniProt

complete

enables

GO:0052689

carboxylic ester hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR023508

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000087140

C

Seeded From UniProt

complete

enables

GO:0052689

carboxylic ester hydrolase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000087140

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0052689

carboxylic ester hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0719

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Kanaya, S et al. (1998) An esterase from Escherichia coli with a sequence similarity to hormone-sensitive lipase. Biochem. J. 332 ( Pt 1) 75-80 PubMed GONUTS page
  2. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Mandrich, L et al. (2002) The Aes protein and the monomeric alpha-galactosidase from Escherichia coli form a non-covalent complex. Implications for the regulation of carbohydrate metabolism. J. Biol. Chem. 277 48241-7 PubMed GONUTS page
  4. Joly, N et al. (2002) The Aes protein directly controls the activity of MalT, the central transcriptional activator of the Escherichia coli maltose regulon. J. Biol. Chem. 277 16606-13 PubMed GONUTS page