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ECOLI:ACPS

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Species (Taxon ID) Escherichia coli (strain K12). (83333)
Gene Name(s) acpS (ECO:0000255 with HAMAP-Rule:MF_00101) (synonyms: dpj)
Protein Name(s) Holo-[acyl-carrier-protein] synthase (ECO:0000255 with HAMAP-Rule:MF_00101)

Holo-ACP synthase (ECO:0000255 with HAMAP-Rule:MF_00101) 4'-phosphopantetheinyl transferase AcpS (ECO:0000255 with HAMAP-Rule:MF_00101)

External Links
UniProt P24224
EMBL M76470
M74526
D64044
U36841
U00096
AP009048
PIR B42294
RefSeq NP_417058.1
YP_490791.1
ProteinModelPortal P24224
SMR P24224
DIP DIP-9047N
IntAct P24224
MINT MINT-1256571
STRING 511145.b2563
PaxDb P24224
PRIDE P24224
EnsemblBacteria AAC75616
BAE76739
GeneID 12931604
947037
KEGG ecj:Y75_p2516
eco:b2563
PATRIC 32120525
EchoBASE EB0243
EcoGene EG10247
eggNOG COG0736
HOGENOM HOG000014316
InParanoid P24224
KO K00997
OMA FTHRCFT
OrthoDB EOG6384R9
PhylomeDB P24224
BioCyc EcoCyc:HOLO-ACP-SYNTH-MONOMER
ECOL316407:JW2547-MONOMER
MetaCyc:HOLO-ACP-SYNTH-MONOMER
PRO PR:P24224
Proteomes UP000000318
UP000000625
Genevestigator P24224
GO GO:0005737
GO:0008897
GO:0000287
GO:0016740
GO:0006633
GO:0009059
GO:0018070
Gene3D 3.90.470.20
HAMAP MF_00101
InterPro IPR008278
IPR002582
IPR004568
Pfam PF01648
ProDom PD004282
SUPFAM SSF56214
TIGRFAMs TIGR00516
TIGR00556

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0018070

peptidyl-serine phosphopantetheinylation

PMID:14294075[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008897

holo-[acyl-carrier-protein] synthase activity

PMID:7559576[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

PMID:7559576[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002582
InterPro:IPR004568
InterPro:IPR008278
InterPro:IPR037143

F

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002582
InterPro:IPR004568

P

Seeded From UniProt

complete

enables

GO:0008897

holo-[acyl-carrier-protein] synthase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002582
InterPro:IPR004568
InterPro:IPR008278
InterPro:IPR037143

F

Seeded From UniProt

complete

enables

GO:0008897

holo-[acyl-carrier-protein] synthase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.8.7

F

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000076456

F

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000076456

P

Seeded From UniProt

complete

enables

GO:0008897

holo-[acyl-carrier-protein] synthase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000076456

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000076456

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

PMID:7559576[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006631

fatty acid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0276

P

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

involved_in

GO:0006633

fatty acid biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0275

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. MAJERUS, PW et al. (1965) ACYL CARRIER PROTEIN. IV. THE IDENTIFICATION OF 4'-PHOSPHOPANTETHEINE AS THE PROSTHETIC GROUP OF THE ACYL CARRIER PROTEIN. Proc. Natl. Acad. Sci. U.S.A. 53 410-7 PubMed GONUTS page
  2. 2.0 2.1 2.2 Lambalot, RH & Walsh, CT (1995) Cloning, overproduction, and characterization of the Escherichia coli holo-acyl carrier protein synthase. J. Biol. Chem. 270 24658-61 PubMed GONUTS page