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ECOLI:ACKA
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | ackA (ECO:0000255 with HAMAP-Rule:MF_00020) (synonyms: ack) | |
| Protein Name(s) | Acetate kinase (ECO:0000255 with HAMAP-Rule:MF_00020)
Acetokinase (ECO:0000255 with HAMAP-Rule:MF_00020) | |
| External Links | ||
| UniProt | P0A6A3 | |
| EMBL | M22956 D17576 U00096 AP009048 | |
| PIR | JT0498 | |
| RefSeq | NP_416799.1 YP_490538.1 | |
| PDB | 1LRG | |
| PDBsum | 1LRG | |
| ProteinModelPortal | P0A6A3 | |
| SMR | P0A6A3 | |
| DIP | DIP-9042N | |
| IntAct | P0A6A3 | |
| STRING | 511145.b2296 | |
| SWISS-2DPAGE | P0A6A3 | |
| PaxDb | P0A6A3 | |
| PRIDE | P0A6A3 | |
| EnsemblBacteria | AAC75356 BAA16135 | |
| GeneID | 12932696 946775 | |
| KEGG | ecj:Y75_p2262 eco:b2296 | |
| PATRIC | 32119963 | |
| EchoBASE | EB0026 | |
| EcoGene | EG10027 | |
| eggNOG | COG0282 | |
| HOGENOM | HOG000288398 | |
| InParanoid | P0A6A3 | |
| KO | K00925 | |
| OMA | KIITCHI | |
| OrthoDB | EOG69975F | |
| PhylomeDB | P0A6A3 | |
| BioCyc | EcoCyc:ACETATEKINA-MONOMER ECOL316407:JW2293-MONOMER MetaCyc:ACETATEKINA-MONOMER | |
| SABIO-RK | P0A6A3 | |
| UniPathway | UPA00340 | |
| PRO | PR:P0A6A3 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0A6A3 | |
| GO | GO:0005829 GO:0016020 GO:0008776 GO:0005524 GO:0000287 GO:0008270 GO:0019413 GO:0006083 GO:0006085 GO:0042710 GO:0019542 | |
| HAMAP | MF_00020 | |
| InterPro | IPR004372 IPR000890 IPR023865 | |
| PANTHER | PTHR21060 | |
| Pfam | PF00871 | |
| PIRSF | PIRSF000722 | |
| PRINTS | PR00471 | |
| TIGRFAMs | TIGR00016 | |
| PROSITE | PS01075 PS01076 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0003922 |
GMP synthase (glutamine-hydrolyzing) activity |
ECO:0000315 |
F |
Table 2 shows that ackA had little effect on the wild type when considering the synthesis of glutamine synthetase. |
complete | |||||
|
involved_in |
GO:0044011 |
single-species biofilm formation on inanimate substrate |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006083 |
acetate metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019542 |
propionate biosynthetic process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
EcoliWiki:tdcD |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019413 |
acetate biosynthetic process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
EcoliWiki:tdcD |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008776 |
acetate kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006082 |
organic acid metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016774 |
phosphotransferase activity, carboxyl group as acceptor |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008776 |
acetate kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008776 |
acetate kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000037499 |
F |
Seeded From UniProt |
complete | ||
| GO:0006083 |
acetate metabolic process |
ECO:0000315 |
P |
Fig 1: showed decreased acetate production in the mutant phenotype. |
complete | |||||
| GO:0044011 |
single-species biofilm formation on inanimate substrate |
ECO:0000315 |
P |
Fig. 6: formation of microcolonies and pellicle |
complete | |||||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000037499 |
P |
Seeded From UniProt |
complete | ||
| GO:0008776 |
acetate kinase activity |
ECO:0000315 |
F |
Table 1 |
complete | |||||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000037499 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000037499 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006085 |
acetyl-CoA biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00340 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Feng, J et al. (1992) Role of phosphorylated metabolic intermediates in the regulation of glutamine synthetase synthesis in Escherichia coli. J. Bacteriol. 174 6061-70 PubMed GONUTS page
- ↑ 2.0 2.1 Wolfe, AJ et al. (2003) Evidence that acetyl phosphate functions as a global signal during biofilm development. Mol. Microbiol. 48 977-88 PubMed GONUTS page
- ↑ 3.0 3.1 Brown, TD et al. (1977) The enzymic interconversion of acetate and acetyl-coenzyme A in Escherichia coli. J. Gen. Microbiol. 102 327-36 PubMed GONUTS page
- ↑ 4.0 4.1 Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed GONUTS page
- ↑ 5.0 5.1 Hesslinger, C et al. (1998) Novel keto acid formate-lyase and propionate kinase enzymes are components of an anaerobic pathway in Escherichia coli that degrades L-threonine to propionate. Mol. Microbiol. 27 477-92 PubMed GONUTS page
- ↑ 6.0 6.1 Matsuyama, A et al. (1989) Cloning, expression, and nucleotide sequence of the Escherichia coli K-12 ackA gene. J. Bacteriol. 171 577-80 PubMed GONUTS page
- ↑ Katayama, A et al. (2002) Systematic search for zinc-binding proteins in Escherichia coli. Eur. J. Biochem. 269 2403-13 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
- ↑ Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page
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