ECOK1:LUXS

Species (Taxon ID)	Escherichia coli O1:K1 / APEC. (405955)
Gene Name(s)	luxS (ECO:0000255 with HAMAP-Rule:MF_00091)
Protein Name(s)	S-ribosylhomocysteine lyase (ECO:0000255 with HAMAP-Rule:MF_00091) AI-2 synthesis protein (ECO:0000255 with HAMAP-Rule:MF_00091) Autoinducer-2 production protein LuxS (ECO:0000255 with HAMAP-Rule:MF_00091)
External Links
UniProt	A1AEN2
EMBL	CP000468
RefSeq	YP_853882.1
ProteinModelPortal	A1AEN2
SMR	A1AEN2
STRING	405955.APECO1_3834
BindingDB	A1AEN2
PRIDE	A1AEN2
EnsemblBacteria	ABJ02122
GeneID	4493105
KEGG	ecv:APECO1_3834
PATRIC	18217495
eggNOG	COG1854
HOGENOM	HOG000040371
KO	K07173
OMA	KQPNQDH
OrthoDB	EOG68WRBM
Proteomes	UP000008216
GO	GO:0005506 GO:0043768 GO:0009372
Gene3D	3.30.1360.80
HAMAP	MF_00091
InterPro	IPR011249 IPR003815
Pfam	PF02664
PIRSF	PIRSF006160
PRINTS	PR01487
ProDom	PD013172
SUPFAM	SSF63411

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0009372	quorum sensing	PMID:23046700	ECO:0000315			P		Figure 3 shows that the mutant strain without the LuxS gene produces much less AI-2. AI-2 is a universal signaling molecule produced by many different types of bacterial to mediate quorum sensing.	complete CACAO 10055
	GO:2000145	regulation of cell motility	PMID:23046700	ECO:0000315			P		Figure 4 shows that the mutant strain without the LuxS gene exhibits much less motility than the wild-type strain.	complete CACAO 10063
involved_in	GO:2000145	regulation of cell motility	PMID:23046700	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0009372	quorum sensing	PMID:23046700	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011249	F		Seeded From UniProt	complete
enables	GO:0005506	iron ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003815 InterPro:IPR037005	F		Seeded From UniProt	complete
involved_in	GO:0009372	quorum sensing	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003815 InterPro:IPR037005	P		Seeded From UniProt	complete
enables	GO:0043768	S-ribosylhomocysteine lyase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003815 InterPro:IPR037005	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011249	F		Seeded From UniProt	complete
enables	GO:0043768	S-ribosylhomocysteine lyase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:4.4.1.21	F		Seeded From UniProt	complete
enables	GO:0043768	S-ribosylhomocysteine lyase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000076351	F		Seeded From UniProt	complete
involved_in	GO:0009372	quorum sensing	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000076351	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
involved_in	GO:0009372	quorum sensing	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0673	P		Seeded From UniProt	complete
enables	GO:0016829	lyase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0456	F		Seeded From UniProt	complete
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References

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