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ECOBW:C4ZT83

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Species (Taxon ID) Escherichia coli (strain K12 / MC4100 / BW2952). (595496)
Gene Name(s) arcA (ECO:0000313 with EMBL:ACR62852.1)
Protein Name(s) DNA-binding response regulator in two-component regulatory system with ArcB or CpxA (ECO:0000313 with EMBL:ACR62852.1)
External Links
UniProt C4ZT83
EMBL CP001396
RefSeq YP_002929284.1
ProteinModelPortal C4ZT83
SMR C4ZT83
STRING 595496.BWG_4093
EnsemblBacteria ACR62852
GeneID 7953998
KEGG ebw:BWG_4093
PATRIC 18278085
eggNOG COG0745
HOGENOM HOG000034819
KO K07773
OMA FLECEGF
OrthoDB EOG6G4VQG
BioCyc ECOL595496:GI18-4266-MONOMER
Proteomes UP000001478
GO GO:0003677
GO:0000160
GO:0006355
GO:0006351
Gene3D 1.10.10.10
InterPro IPR011006
IPR001867
IPR016032
IPR001789
IPR011991
Pfam PF00072
PF00486
SMART SM00448
SM00862
SUPFAM SSF46894
SSF52172
PROSITE PS50110

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000156

phosphorelay response regulator activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001789
InterPro:IPR001867
InterPro:IPR016032

F

Seeded From UniProt

complete

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001789
InterPro:IPR001867
InterPro:IPR016032

P

Seeded From UniProt

complete

GO:0000160

phosphorelay signal transduction system

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0902

P

Seeded From UniProt

complete

GO:0003677

DNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001867
InterPro:IPR016032

F

Seeded From UniProt

complete

GO:0003677

DNA binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

GO:0005622

intracellular

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016032

C

Seeded From UniProt

complete

GO:0006351

transcription, DNA-templated

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

Seeded From UniProt

complete

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001789
InterPro:IPR001867
InterPro:IPR016032

P

Seeded From UniProt

complete

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

Seeded From UniProt

complete

GO:0006355

regulation of transcription, DNA-dependent

PMID:10071223[1]

IDA: Inferred from Direct Assay

P

Figure 2. EMSA of arcA and arcA-P binding to aldA promoter. This figure shows arcA binds to the aldA promoter but Table 2 is needed to show that this binding regulates transcription.

Table 2. The arcA binding region of the aldA promoter was mutated. This mutation relieved the aldA promoter from arcA repression during anaerobic conditions.


complete
CACAO 2981

GO:0035556

intracellular signal transduction

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001789
InterPro:IPR001867
InterPro:IPR016032

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Pellicer, MT et al. (1999) A mutational study of the ArcA-P binding sequences in the aldA promoter of Escherichia coli. Mol. Gen. Genet. 261 170-6 PubMed GONUTS page