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ECO5T:C6V2D0
Contents
| Species (Taxon ID) | Escherichia coli O157:H7 (strain TW14359 / EHEC). (544404) | |
| Gene Name(s) | nleH1 (ECO:0000313 with EMBL:ACT70726.1) | |
| Protein Name(s) | Non-LEE-encoded type III secreted effector (ECO:0000313 with EMBL:ACT70726.1) | |
| External Links | ||
| UniProt | C6V2D0 | |
| EMBL | CP001368 | |
| RefSeq | YP_003076802.1 | |
| EnsemblBacteria | ACT70726 | |
| GeneID | 8215433 | |
| KEGG | etw:ECSP_0867 | |
| PATRIC | 18385618 | |
| HOGENOM | HOG000033734 | |
| KO | K16042 | |
| OMA | NISERSW | |
| OrthoDB | EOG64R62N | |
| BioCyc | ECOL544404:GKCX-866-MONOMER | |
| Proteomes | UP000002056 | |
| GO | GO:0016772 GO:0042326 | |
| InterPro | IPR011009 | |
| SUPFAM | SSF56112 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000060 |
protein import into nucleus, translocation |
IDA: Inferred from Direct Assay |
P |
Figure 2B. CRKL is necessary for NheH1 to inhibit nuclear translocation |
complete | |||
| GO:0006468 |
protein phosphorylation |
IDA: Inferred from Direct Assay |
P |
Figure 1B. Recombinant NleH1, but not NleH1(K159A) phosphorylates recombinant CRKL in vitro. |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Pham, TH et al. (2013) Escherichia coli virulence protein NleH1 interaction with the v-Crk sarcoma virus CT10 oncogene-like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/nuclear factor κB (NF-κB) pathway. J. Biol. Chem. 288 34567-74 PubMed GONUTS page
