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ECO57:HLYE

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Species (Taxon ID) Escherichia coli O157:H7. (83334)
Gene Name(s) hlyE (synonyms: clyA, sheA)
Protein Name(s) Hemolysin E

Cytotoxin ClyA Silent hemolysin SheA

External Links
UniProt Q9REB3
EMBL AJ238954
AE005174
BA000007
PIR E85696
E90838
RefSeq NP_287421.1
NP_309704.1
ProteinModelPortal Q9REB3
SMR Q9REB3
STRING 155864.Z1944
EnsemblBacteria AAG56033
BAB35100
GeneID 913196
959895
KEGG ece:Z1944
ecs:ECs1677
PATRIC 18352606
eggNOG NOG72512
HOGENOM HOG000051663
KO K11139
OMA KTVQNFF
OrthoDB EOG6XWV0P
BioCyc ECOL386585:GJFA-1659-MONOMER
Proteomes UP000000558
UP000002519
GO GO:0020002
GO:0016021
GO:0042597
GO:0044179
GO:0009405
InterPro IPR027018
Pfam PF06109

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0009405

pathogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027018

P

Seeded From UniProt

complete

involved_in

GO:0044179

hemolysis in other organism

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027018

P

Seeded From UniProt

complete

GO:0019836

hemolysis by symbiont of host erythrocytes

PMID:14996792[1]

ECO:0000314

P

Fig 2: FNR and CRP make positive contributions, whereas H-NS acts negatively under these conditions.

complete
CACAO 10724

involved_in

GO:0019835

cytolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0204

P

Seeded From UniProt

complete

involved_in

GO:0044179

hemolysis in other organism

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0354

P

Seeded From UniProt

complete

part_of

GO:0033644

host cell membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1043

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0042597

periplasmic space

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0574
UniProtKB-SubCell:SL-0200

C

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0020002

host cell plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1032
UniProtKB-SubCell:SL-0375

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Wyborn, NR et al. (2004) Regulation of Escherichia coli hemolysin E expression by H-NS and Salmonella SlyA. J. Bacteriol. 186 1620-8 PubMed GONUTS page