EBVB9:BRRF1

Species (Taxon ID)	Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4). (10377)
Gene Name(s)	No Information Provided.
Protein Name(s)	Transcriptional activator BRRF1
External Links
UniProt	P03207
EMBL	V01555 AJ507799
PIR	H43042
RefSeq	YP_401675.1
BioGrid	971770
GeneID	3783728
Proteomes	UP000007640
GO	GO:0006355 GO:0019046 GO:0006351
InterPro	IPR006878
Pfam	PF04793

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0019046	release from viral latency	PMID:21325409	ECO:0000315			P		Figure 1 A-C: Three different cell lines were transfected with plasmids for the over-expression of Na (which is the product of gene BRRF1) as well as control plasmids with no over-expression of Na. To see if Na initiated lysis in the cells in which Na was overproduced, immunoassays were performed to search for lytic cell products. The proteins searched for include BMRF1, Z protein, R protein, Na (through FLAG), and β-actin. In all three types of cells with plasmids over-expressing BRRF1, these lytic proteins were found in a greater amount than in the cells without the over-expression plasmids. Expression of BRRF1 leads to a product that affects maintenance of viral latency. The evidence code is IMP because there is over-expression of the gene. Presence of the gene product resulted in an increase in specific lytic proteins measured by an immunoblot assay.	complete CACAO 7262
involved_in	GO:0019046	release from viral latency	PMID:21325409	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
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References

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