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DROME:XDH
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | ry (synonyms: XDH) | |
| Protein Name(s) | Xanthine dehydrogenase
XD Protein rosy locus | |
| External Links | ||
| UniProt | P10351 | |
| EMBL | Y00308 AE014297 BT015293 AY094689 | |
| PIR | S07245 | |
| RefSeq | NP_524337.1 | |
| UniGene | Dm.2436 | |
| ProteinModelPortal | P10351 | |
| SMR | P10351 | |
| IntAct | P10351 | |
| PaxDb | P10351 | |
| EnsemblMetazoa | FBtr0082704 | |
| GeneID | 41605 | |
| KEGG | dme:Dmel_CG7642 | |
| CTD | 41605 | |
| FlyBase | FBgn0003308 | |
| eggNOG | COG4630 | |
| GeneTree | ENSGT00390000003772 | |
| InParanoid | P10351 | |
| KO | K00106 | |
| OMA | FHMENSY | |
| OrthoDB | EOG7QRQSZ | |
| PhylomeDB | P10351 | |
| Reactome | REACT_180681 | |
| GenomeRNAi | 41605 | |
| NextBio | 824612 | |
| PRO | PR:P10351 | |
| Proteomes | UP000000803 | |
| Bgee | P10351 | |
| GO | GO:0005875 GO:0005777 GO:0051537 GO:0009055 GO:0050660 GO:0005506 GO:0043546 GO:0008762 GO:0004854 GO:0004855 GO:0006525 GO:0048072 GO:0008340 GO:0006650 GO:0006144 GO:0006206 GO:0006568 GO:0009115 | |
| Gene3D | 1.10.150.120 3.10.20.30 3.30.365.10 3.30.43.10 3.30.465.10 3.90.1170.50 | |
| InterPro | IPR002888 IPR001041 IPR006058 IPR000674 IPR016208 IPR008274 IPR012675 IPR005107 IPR016169 IPR016166 IPR016167 IPR002346 IPR022407 IPR014307 | |
| Pfam | PF01315 PF02738 PF03450 PF00941 PF00111 PF01799 | |
| PIRSF | PIRSF000127 | |
| SMART | SM01008 SM01092 | |
| SUPFAM | SSF47741 SSF54292 SSF54665 SSF55447 SSF56003 SSF56176 | |
| TIGRFAMs | TIGR02963 | |
| PROSITE | PS00197 PS51085 PS51387 PS00559 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043546 |
molybdopterin cofactor binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043546 |
molybdopterin cofactor binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009115 |
xanthine catabolic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004854 |
xanthine dehydrogenase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000225632 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009115 |
xanthine catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000225632 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88035 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004854 |
xanthine dehydrogenase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98973 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006525 |
arginine metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006568 |
tryptophan metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006650 |
glycerophospholipid metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006206 |
pyrimidine nucleobase metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006144 |
purine nucleobase metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008340 |
determination of adult lifespan |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004854 |
xanthine dehydrogenase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0022900 |
electron transport chain |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0009055 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004854 |
xanthine dehydrogenase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004855 |
xanthine oxidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005506 |
iron ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0009055 |
electron transfer activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002346 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0043546 |
molybdopterin cofactor binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051536 |
iron-sulfur cluster binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002346 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0071949 |
FAD binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004854 |
xanthine dehydrogenase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048072 |
compound eye pigmentation |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005777 |
peroxisome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051536 |
iron-sulfur cluster binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051537 |
2 iron, 2 sulfur cluster binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Kamleh, MA et al. (2008) Metabolomic profiling of Drosophila using liquid chromatography Fourier transform mass spectrometry. FEBS Lett. 582 2916-22 PubMed GONUTS page
- ↑ Simonsen, A et al. (2007) Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles. Genetics 176 1283-97 PubMed GONUTS page
- ↑ Marelja, Z et al. (2018) Iron Sulfur and Molybdenum Cofactor Enzymes Regulate the Life Cycle by Controlling Cell Metabolism. Front Physiol 9 50 PubMed GONUTS page
- ↑ Reaume, AG et al. (1991) The rosy locus in Drosophila melanogaster: xanthine dehydrogenase and eye pigments. Genetics 129 1099-109 PubMed GONUTS page
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