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DROME:TPM2

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) Tm2 (synonyms: TmI)
Protein Name(s) Tropomyosin-2

Tropomyosin I

External Links
UniProt P09491
EMBL K02622
K02623
K02622
K03277
K03277
AE014297
AE014297
AE014297
AY071087
BT029283
BT044580
X02220
PIR A25624
B25624
RefSeq NP_001262592.1
NP_001262593.1
NP_001287337.1
NP_524361.4
NP_732012.1
NP_732013.2
UniGene Dm.2422
ProteinModelPortal P09491
SMR P09491
BioGrid 66917
DIP DIP-21556N
IntAct P09491
STRING 7227.FBpp0089270
Allergome 1517
4080
4174
4175
PaxDb P09491
PRIDE P09491
EnsemblMetazoa FBtr0083080
GeneID 41853
KEGG dme:Dmel_CG4843
UCSC CG4843-RB
CTD 41853
FlyBase FBgn0004117
eggNOG NOG304012
GeneTree ENSGT00550000074494
InParanoid P09491
KO K10374
OMA TINHMSQ
OrthoDB EOG7673C8
PhylomeDB P09491
Reactome REACT_211028
GenomeRNAi 41853
NextBio 825930
PRO PR:P09491
Proteomes UP000000803
Bgee P09491
ExpressionAtlas P09491
GO GO:0003779
GO:0007507
InterPro IPR000533
Pfam PF00261
PRINTS PR00194
PROSITE PS00326

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0051015

actin filament binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003721
MGI:MGI:1890149
MGI:MGI:2449202
MGI:MGI:98809
PANTHER:PTN000443979
PomBase:SPAC27F1.02c
RGD:1559479
RGD:3898
RGD:3899
WB:WBGene00002978

F

Seeded From UniProt

complete

involved_in

GO:0007015

actin filament organization

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000443979
WB:WBGene00002978

P

Seeded From UniProt

complete

part_of

GO:0005884

actin filament

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000443979
PomBase:SPAC27F1.02c

C

Seeded From UniProt

complete

involved_in

GO:0060298

positive regulation of sarcomere organization

PMID:26293307[2]

ECO:0000316

genetic interaction evidence used in manual assertion

FB:FBgn0286786

P

Seeded From UniProt

complete

involved_in

GO:0007507

heart development

PMID:16432241[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003779

actin binding

PMID:10908588[4]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Williams, J et al. (2015) Noncanonical roles for Tropomyosin during myogenesis. Development 142 3440-52 PubMed GONUTS page
  3. Wolf, MJ et al. (2006) Drosophila as a model for the identification of genes causing adult human heart disease. Proc. Natl. Acad. Sci. U.S.A. 103 1394-9 PubMed GONUTS page
  4. Goldstein, LS & Gunawardena, S (2000) Flying through the drosophila cytoskeletal genome. J. Cell Biol. 150 F63-8 PubMed GONUTS page