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DROME:SMSR1
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | SMSr | |
| Protein Name(s) | Sphingomyelin synthase-related 1
Ceramide phosphoethanolamine synthase CPE synthase | |
| External Links | ||
| UniProt | Q9VS60 | |
| EMBL | AE014296 AE014296 AY051605 BT003174 | |
| RefSeq | NP_648114.1 | |
| UniGene | Dm.874 | |
| ProteinModelPortal | Q9VS60 | |
| BioGrid | 64262 | |
| MINT | MINT-1647866 | |
| STRING | 7227.FBpp0076580 | |
| PaxDb | Q9VS60 | |
| EnsemblMetazoa | FBtr0076870 | |
| GeneID | 38823 | |
| KEGG | dme:Dmel_CG32380 | |
| UCSC | CG32380-RA | |
| CTD | 38823 | |
| FlyBase | FBgn0052380 | |
| eggNOG | NOG259509 | |
| GeneTree | ENSGT00390000001630 | |
| InParanoid | Q9VS60 | |
| OMA | RAYRIWS | |
| OrthoDB | EOG7NCV32 | |
| PhylomeDB | Q9VS60 | |
| BioCyc | FLY:FBGN0052380-MONOMER | |
| ChiTaRS | SMSr | |
| GenomeRNAi | 38823 | |
| NextBio | 810560 | |
| PRO | PR:Q9VS60 | |
| Proteomes | UP000000803 | |
| Bgee | Q9VS60 | |
| GO | GO:0030176 GO:0016021 GO:0047493 GO:0033188 GO:0046513 GO:0007030 GO:0060305 GO:2000303 GO:0006686 | |
| Gene3D | 1.10.150.50 | |
| InterPro | IPR001660 IPR013761 IPR025749 | |
| Pfam | PF14360 | |
| SUPFAM | SSF47769 | |
| PROSITE | PS50105 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:2000303 |
regulation of ceramide biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0047493 |
ceramide cholinephosphotransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046513 |
ceramide biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0033188 |
sphingomyelin synthase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030176 |
integral component of endoplasmic reticulum membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006686 |
sphingomyelin biosynthetic process |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0047493 |
ceramide cholinephosphotransferase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0052380 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0046513 |
ceramide biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0052380 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0033188 |
sphingomyelin synthase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0052380 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030176 |
integral component of endoplasmic reticulum membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0052380 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030173 |
integral component of Golgi membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000480004 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030148 |
sphingolipid biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001083550 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000480004 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007030 |
Golgi organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060305 |
regulation of cell diameter |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006665 |
sphingolipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Vacaru, AM et al. (2009) Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER. J. Cell Biol. 185 1013-27 PubMed GONUTS page
- ↑ 2.0 2.1 Huitema, K et al. (2004) Identification of a family of animal sphingomyelin synthases. EMBO J. 23 33-44 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 4.0 4.1 Kondylis, V et al. (2011) Identification of ER proteins involved in the functional organisation of the early secretory pathway in Drosophila cells by a targeted RNAi screen. PLoS ONE 6 e17173 PubMed GONUTS page
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