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DROME:Q9W4I7

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided.
Protein Name(s) Partner of numb (ECO:0000313 with EMBL:AAF45964.1)

RE65495p (ECO:0000313 with EMBL:AAL68323.1)

External Links
UniProt Q9W4I7
EMBL AE014298
AY075515
RefSeq NP_525072.2
UniGene Dm.1681
EnsemblMetazoa FBtr0070681
GeneID 31394
KEGG dme:Dmel_CG3346
UCSC CG3346-RA
CTD 31394
FlyBase FBgn0025739
OMA RYQLELE
PhylomeDB Q9W4I7
GenomeRNAi 31394
NextBio 773427
Proteomes UP000000803
GO GO:0045180
GO:0045178
GO:0005938
GO:0005737
GO:0055059
GO:0008105
GO:0035050

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

PMID:16243032[1]

IDA: Inferred from Direct Assay

C

Pon rapidly exchange between a cytoplasmic pool and the cell cortex and that preferential recruitment from the cytoplasm is responsible for its asymmetric distribution during mitosis. This is evident in Figure 1 in which distinct phases of Pon asymmetric localization are discussed. Figure 1E in particular shows the direct recruitment model from the cytoplasm.

complete
CACAO 7557

GO:0005737

cytoplasm

PMID:16243032[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

PMID:16243032[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005938

cell cortex

PMID:16243032[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0008105

asymmetric protein localization

PMID:10887088[2]

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0035050

embryonic heart tube development

PMID:22814603[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0015396

P

Seeded From UniProt

complete

GO:0035050

embryonic heart tube development

PMID:22814603[3]

IGI: Inferred from Genetic Interaction

FB:FBgn0029504

P

Seeded From UniProt

complete

GO:0045178

basal part of cell

PMID:12185850[4]

TAS: Traceable Author Statement

C

Seeded From UniProt

complete

GO:0045180

basal cortex

PMID:11697883[5]

NAS: Non-traceable Author Statement

C

Seeded From UniProt

complete

GO:0045180

basal cortex

PMID:12447381[6]

NAS: Non-traceable Author Statement

C

Seeded From UniProt

complete

GO:0055059

asymmetric neuroblast division

PMID:12137730[7]

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Mayer, B et al. (2005) Quantitative analysis of protein dynamics during asymmetric cell division. Curr. Biol. 15 1847-54 PubMed GONUTS page
  2. Cheah, PY et al. (2000) Jumeaux, a novel Drosophila winged-helix family protein, is required for generating asymmetric sibling neuronal cell fates. Development 127 3325-35 PubMed GONUTS page
  3. 3.0 3.1 Ahmad, SM et al. (2012) Two forkhead transcription factors regulate the division of cardiac progenitor cells by a Polo-dependent pathway. Dev. Cell 23 97-111 PubMed GONUTS page
  4. Gönczy, P (2002) Mechanisms of spindle positioning: focus on flies and worms. Trends Cell Biol. 12 332-9 PubMed GONUTS page
  5. Schaefer, M & Knoblich, JA (2001) Protein localization during asymmetric cell division. Exp. Cell Res. 271 66-74 PubMed GONUTS page
  6. Cayouette, M & Raff, M (2002) Asymmetric segregation of Numb: a mechanism for neural specification from Drosophila to mammals. Nat. Neurosci. 5 1265-9 PubMed GONUTS page
  7. Tree, DR et al. (2002) A three-tiered mechanism for regulation of planar cell polarity. Semin. Cell Dev. Biol. 13 217-24 PubMed GONUTS page