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DROME:Q9VYT4

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided.
Protein Name(s) ATP7, isoform B (ECO:0000313 with EMBL:AAF48104.3)

ATP7, isoform C (ECO:0000313 with EMBL:AGB95309.1)

External Links
UniProt Q9VYT4
EMBL AE014298
AE014298
RefSeq NP_001259466.1
NP_572756.3
UniGene Dm.18759
SMR Q9VYT4
MINT MINT-324878
STRING 7227.FBpp0271765
EnsemblMetazoa FBtr0273257
GeneID 32142
KEGG dme:Dmel_CG1886
UCSC CG1886-RB
CTD 32142
FlyBase FBgn0030343
GeneTree ENSGT00730000111636
KO K17686
OMA MDGVEAN
OrthoDB EOG7C2R0G
PhylomeDB Q9VYT4
Reactome REACT_232261
GenomeRNAi 32142
NextBio 777072
PRO PR:Q9VYT4
Proteomes UP000000803
Bgee Q9VYT4
GO GO:0005737
GO:0016021
GO:0005886
GO:0005524
GO:0005507
GO:0005375
GO:0004008
GO:0048085
GO:0006878
GO:0035434
GO:0048066
GO:0002164
GO:0055065
Gene3D 2.70.150.10
3.40.1110.10
3.40.50.1000
InterPro IPR023299
IPR018303
IPR008250
IPR023214
IPR017969
IPR006121
IPR006122
IPR027256
IPR001757
Pfam PF00122
PF00403
PF00702
PRINTS PR00119
SUPFAM SSF55008
SSF56784
SSF81660
TIGRFAMs TIGR01525
TIGR01494
TIGR00003
PROSITE PS00154
PS01047
PS50846

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008250
InterPro:IPR023299

F

Seeded From UniProt

complete

GO:0000166

nucleotide binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

GO:0002164

larval development

PMID:16251357[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0004008

copper-exporting ATPase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:3.6.3.4

F

Seeded From UniProt

complete

GO:0005375

copper ion transmembrane transporter activity

PMID:15239669[2]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

complete

GO:0005507

copper ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006122

F

Seeded From UniProt

complete

GO:0055070

copper ion homeostasis

PMID:20038716[3]

IMP: Inferred from Mutant Phenotype

P

Figure 2b shows partial silencing of ATP7 reduces the Cu content of the head and body

complete
CACAO 6642

GO:0005507

copper ion binding

PMID:15239669[2]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P35670

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

GO:0005737

cytoplasm

PMID:16251357[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

PMID:16251357[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0006812

cation transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027256

P

Seeded From UniProt

complete

GO:0006878

cellular copper ion homeostasis

PMID:15239669[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0008152

metabolic process

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

P

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001757
InterPro:IPR027256

C

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

GO:0016787

hydrolase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

GO:0019829

cation-transporting ATPase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027256

F

Seeded From UniProt

complete

GO:0030001

metal ion transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006121
InterPro:IPR017969

P

Seeded From UniProt

complete

GO:0035434

copper ion transmembrane transport

PMID:15239669[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0046872

metal ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006121
InterPro:IPR008250
InterPro:IPR017969

F

Seeded From UniProt

complete

GO:0048066

developmental pigmentation

PMID:16251357[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0048085

adult chitin-containing cuticle pigmentation

PMID:16251357[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0055065

metal ion homeostasis

PMID:20038716[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0055070

copper ion homeostasis

PMID:20038716[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0060003

copper ion export

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:3.6.3.4

P

Seeded From UniProt

complete

GO:0098655

cation transmembrane transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR027256

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Norgate, M et al. (2006) Essential roles in development and pigmentation for the Drosophila copper transporter DmATP7. Mol. Biol. Cell 17 475-84 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Southon, A et al. (2004) Copper homoeostasis in Drosophila melanogaster S2 cells. Biochem. J. 383 303-9 PubMed GONUTS page
  3. 3.0 3.1 3.2 Bahadorani, S et al. () A Drosophila model of Menkes disease reveals a role for DmATP7 in copper absorption and neurodevelopment. Dis Model Mech 3 84-91 PubMed GONUTS page