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DROME:Q9VMH3

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided. (synonyms: stathmin (ECO:0000313 with EMBL:AAL28619.1))
Protein Name(s) LD04103p (ECO:0000313 with EMBL:AAL28619.1)

Stathmin, isoform A (ECO:0000313 with EMBL:AAF52345.2)

External Links
UniProt Q9VMH3
EMBL AE014134
AY061071
RefSeq NP_723158.1
UniGene Dm.3380
SMR Q9VMH3
STRING 7227.FBpp0078828
EnsemblMetazoa FBtr0079198
GeneID 33863
KEGG dme:Dmel_CG31641
UCSC CG31641-RA
CTD 33863
FlyBase FBgn0266521
GeneTree ENSGT00390000003691
KO K04381
GenomeRNAi 33863
NextBio 785671
Proteomes UP000000803
GO GO:0005875
GO:0008017
GO:0015631
GO:0008088
GO:0007298
GO:0008354
GO:0007017
GO:0007399
GO:0031110
InterPro IPR000956
PANTHER PTHR10104
Pfam PF00836
PRINTS PR00345
SUPFAM SSF101494
PROSITE PS51663

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0007399

nervous system development

PMID:22016536[1]

IMP: Inferred from Mutant Phenotype

P

Figure 1: Mutant phenotype results in axon retraction

complete
CACAO 6714

GO:0005829

cytosol

PMID:25294944[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005875

microtubule associated complex

PMID:10908588[3]

ISS: Inferred from Sequence or Structural Similarity

C

Seeded From UniProt

Missing: with/from

GO:0005875

microtubule associated complex

PMID:18433294[4]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0007017

microtubule-based process

PMID:10908588[3]

ISS: Inferred from Sequence or Structural Similarity

P

Seeded From UniProt

Missing: with/from

GO:0007298

border follicle cell migration

PMID:16580994[5]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007298

border follicle cell migration

PMID:22808215[6]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007399

nervous system development

PMID:11854423[7]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0008017

microtubule binding

PMID:10908588[3]

ISS: Inferred from Sequence or Structural Similarity

F

Seeded From UniProt

Missing: with/from

GO:0008088

axon cargo transport

PMID:23840848[8]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0008354

germ cell migration

PMID:11854423[7]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0015631

tubulin binding

PMID:20145240[9]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0031110

regulation of microtubule polymerization or depolymerization

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000956

P

Seeded From UniProt

complete

GO:0031594

neuromuscular junction

PMID:22016536[1]

IMP: Inferred from Mutant Phenotype

C

Seeded From UniProt

complete

GO:0051124

synaptic growth at neuromuscular junction

PMID:22016536[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Graf, ER et al. (2011) Stathmin is required for stability of the Drosophila neuromuscular junction. J. Neurosci. 31 15026-34 PubMed GONUTS page
  2. Lye, CM et al. (2014) Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos. Development 141 4006-17 PubMed GONUTS page
  3. 3.0 3.1 3.2 Goldstein, LS & Gunawardena, S (2000) Flying through the drosophila cytoskeletal genome. J. Cell Biol. 150 F63-8 PubMed GONUTS page
  4. Hughes, JR et al. (2008) A microtubule interactome: complexes with roles in cell cycle and mitosis. PLoS Biol. 6 e98 PubMed GONUTS page
  5. Borghese, L et al. (2006) Systematic analysis of the transcriptional switch inducing migration of border cells. Dev. Cell 10 497-508 PubMed GONUTS page
  6. Yang, N et al. (2012) Microtubules and Lis-1/NudE/dynein regulate invasive cell-on-cell migration in Drosophila. PLoS ONE 7 e40632 PubMed GONUTS page
  7. 7.0 7.1 Ozon, S et al. (2002) Drosophila stathmin: a microtubule-destabilizing factor involved in nervous system formation. Mol. Biol. Cell 13 698-710 PubMed GONUTS page
  8. Duncan, JE et al. (2013) The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila. PLoS ONE 8 e68324 PubMed GONUTS page
  9. Lachkar, S et al. (2010) Drosophila stathmins bind tubulin heterodimers with high and variable stoichiometries. J. Biol. Chem. 285 11667-80 PubMed GONUTS page