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DROME:Q86NW1
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | No Information Provided. (synonyms: Vmat-RC (ECO:0000313 with EMBL:ACL68709.1)) | |
| Protein Name(s) | FI07245p (ECO:0000313 with EMBL:ACL68709.1)
GH16917p (ECO:0000313 with EMBL:AAO39614.1) RH74704p (ECO:0000313 with EMBL:AAR96127.1) Vesicular monoamine transporter, isoform C (ECO:0000313 with EMBL:AAX52707.1) Vesicular monoamine transporter, isoform E (ECO:0000313 with EMBL:AAX52708.1) | |
| External Links | ||
| UniProt | Q86NW1 | |
| EMBL | BT003611 BT011335 AE013599 AE013599 BT056262 | |
| RefSeq | NP_001014524.1 NP_001014526.1 NP_001260956.1 | |
| UniGene | Dm.20853 | |
| SMR | Q86NW1 | |
| EnsemblMetazoa | FBtr0091491 FBtr0091493 FBtr0310062 | |
| GeneID | 3346192 | |
| KEGG | dme:Dmel_CG33528 | |
| UCSC | CG33528-RC | |
| CTD | 3346192 | |
| FlyBase | FBgn0260964 | |
| eggNOG | NOG255549 | |
| GeneTree | ENSGT00390000003851 | |
| KO | K08155 | |
| OrthoDB | EOG79CXZ7 | |
| Reactome | REACT_231589 REACT_238906 REACT_257046 REACT_258601 | |
| GenomeRNAi | 3346192 | |
| NextBio | 849174 | |
| Proteomes | UP000000803 | |
| GO | GO:0016021 GO:0031594 GO:0008021 GO:0015238 GO:0008504 GO:0005430 GO:0015872 GO:0051608 GO:0015844 GO:0015842 | |
| InterPro | IPR011701 IPR020846 IPR004734 | |
| Pfam | PF07690 | |
| SUPFAM | SSF103473 | |
| TIGRFAMs | TIGR00880 | |
| PROSITE | PS50850 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0043195 |
terminal bouton |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000607052 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030672 |
synaptic vesicle membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000607052 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0015842 |
aminergic neurotransmitter loading into synaptic vesicle |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0260964 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008504 |
monoamine transmembrane transporter activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0260964 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006836 |
neurotransmitter transport |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000607052 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005335 |
serotonin:sodium symporter activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000607052 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1904647 |
response to rotenone |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1904340 |
positive regulation of dopaminergic neuron differentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0008021 |
synaptic vesicle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051608 |
histamine transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015872 |
dopamine transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006855 |
drug transmembrane transport |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0015238 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051610 |
serotonin uptake |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005335 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0015238 |
drug transmembrane transporter activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015893 |
drug transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055085 |
transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 Lawal, HO et al. (2010) The Drosophila vesicular monoamine transporter reduces pesticide-induced loss of dopaminergic neurons. Neurobiol. Dis. 40 102-12 PubMed GONUTS page
- ↑ Grygoruk, A et al. (2010) A tyrosine-based motif localizes a Drosophila vesicular transporter to synaptic vesicles in vivo. J. Biol. Chem. 285 6867-78 PubMed GONUTS page
- ↑ Romero-Calderón, R et al. (2008) A glial variant of the vesicular monoamine transporter is required to store histamine in the Drosophila visual system. PLoS Genet. 4 e1000245 PubMed GONUTS page
- ↑ Sang, TK et al. (2007) A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. J. Neurosci. 27 981-92 PubMed GONUTS page
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