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DROME:Q86NW1

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided. (synonyms: Vmat-RC (ECO:0000313 with EMBL:ACL68709.1))
Protein Name(s) FI07245p (ECO:0000313 with EMBL:ACL68709.1)

GH16917p (ECO:0000313 with EMBL:AAO39614.1) RH74704p (ECO:0000313 with EMBL:AAR96127.1) Vesicular monoamine transporter, isoform C (ECO:0000313 with EMBL:AAX52707.1) Vesicular monoamine transporter, isoform E (ECO:0000313 with EMBL:AAX52708.1)

External Links
UniProt Q86NW1
EMBL BT003611
BT011335
AE013599
AE013599
BT056262
RefSeq NP_001014524.1
NP_001014526.1
NP_001260956.1
UniGene Dm.20853
SMR Q86NW1
EnsemblMetazoa FBtr0091491
FBtr0091493
FBtr0310062
GeneID 3346192
KEGG dme:Dmel_CG33528
UCSC CG33528-RC
CTD 3346192
FlyBase FBgn0260964
eggNOG NOG255549
GeneTree ENSGT00390000003851
KO K08155
OrthoDB EOG79CXZ7
Reactome REACT_231589
REACT_238906
REACT_257046
REACT_258601
GenomeRNAi 3346192
NextBio 849174
Proteomes UP000000803
GO GO:0016021
GO:0031594
GO:0008021
GO:0015238
GO:0008504
GO:0005430
GO:0015872
GO:0051608
GO:0015844
GO:0015842
InterPro IPR011701
IPR020846
IPR004734
Pfam PF07690
SUPFAM SSF103473
TIGRFAMs TIGR00880
PROSITE PS50850

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005430

synaptic vesicle amine transmembrane transporter activity

PMID:15849736[1]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0006855

drug transmembrane transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004734

P

Seeded From UniProt

complete

GO:0008021

synaptic vesicle

PMID:20053989[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0008504

monoamine transmembrane transporter activity

PMID:15849736[1]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0015238

drug transmembrane transporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004734

F

Seeded From UniProt

complete

GO:0015842

synaptic vesicle amine transport

PMID:15849736[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0015844

monoamine transport

PMID:15849736[1]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0015872

dopamine transport

PMID:17267552[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0015893

drug transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004734

P

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004734
InterPro:IPR011701

C

Seeded From UniProt

complete

GO:0031594

neuromuscular junction

PMID:15849736[1]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0051608

histamine transport

PMID:18989452[4]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0055085

transmembrane transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011701

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Greer, CL et al. (2005) A splice variant of the Drosophila vesicular monoamine transporter contains a conserved trafficking domain and functions in the storage of dopamine, serotonin, and octopamine. J. Neurobiol. 64 239-58 PubMed GONUTS page
  2. Grygoruk, A et al. (2010) A tyrosine-based motif localizes a Drosophila vesicular transporter to synaptic vesicles in vivo. J. Biol. Chem. 285 6867-78 PubMed GONUTS page
  3. Sang, TK et al. (2007) A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. J. Neurosci. 27 981-92 PubMed GONUTS page
  4. Romero-Calderón, R et al. (2008) A glial variant of the vesicular monoamine transporter is required to store histamine in the Drosophila visual system. PLoS Genet. 4 e1000245 PubMed GONUTS page