GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
DROME:PLU
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | plu | |
| Protein Name(s) | DNA replication inhibitor plutonium | |
| External Links | ||
| UniProt | P42570 | |
| EMBL | U03986 AE013599 | |
| PIR | S41713 | |
| RefSeq | NP_476683.1 | |
| ProteinModelPortal | P42570 | |
| SMR | P42570 | |
| BioGrid | 69325 | |
| DIP | DIP-24015N | |
| IntAct | P42570 | |
| MINT | MINT-769934 | |
| PRIDE | P42570 | |
| EnsemblMetazoa | FBtr0086306 | |
| GeneID | 44848 | |
| KEGG | dme:Dmel_CG9183 | |
| UCSC | CG9183-RA | |
| CTD | 44848 | |
| FlyBase | FBgn0003114 | |
| eggNOG | NOG240093 | |
| InParanoid | P42570 | |
| OMA | NYFGQNA | |
| OrthoDB | EOG7M3J1N | |
| PhylomeDB | P42570 | |
| SignaLink | P42570 | |
| GenomeRNAi | 44848 | |
| NextBio | 837719 | |
| Proteomes | UP000000803 | |
| Bgee | P42570 | |
| ExpressionAtlas | P42570 | |
| GO | GO:0006260 GO:0007343 GO:0008156 GO:0007346 GO:0007338 | |
| Gene3D | 1.25.40.20 | |
| InterPro | IPR002110 IPR020683 | |
| Pfam | PF00023 | |
| SMART | SM00248 | |
| SUPFAM | SSF48403 | |
| PROSITE | PS50297 PS50088 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0045977 |
positive regulation of mitotic cell cycle, embryonic |
ECO:0000314 |
P |
See Figure 5B. Co-expressor with PNG. |
complete | |||||
| GO:0045977 |
positive regulation of mitotic cell cycle, embryonic |
ECO:0000315 |
P |
See the comparisons of the mutant and wild-type genotypes in figure 7. |
complete | |||||
|
involved_in |
GO:0007343 |
egg activation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:1902554 |
serine/threonine protein kinase complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0000826 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008156 |
negative regulation of DNA replication |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007338 |
single fertilization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:1902911 |
protein kinase complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007346 |
regulation of mitotic cell cycle |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Fenger, DD et al. (2000) PAN GU: a protein kinase that inhibits S phase and promotes mitosis in early Drosophila development. Development 127 4763-74 PubMed GONUTS page
- ↑ Tadros, W et al. (2003) Regulation of maternal transcript destabilization during egg activation in Drosophila. Genetics 164 989-1001 PubMed GONUTS page
- ↑ 3.0 3.1 Axton, JM et al. (1994) The inhibitor of DNA replication encoded by the Drosophila gene plutonium is a small, ankyrin repeat protein. EMBO J. 13 462-70 PubMed GONUTS page
- ↑ Hara, M et al. (2017) Control of PNG kinase, a key regulator of mRNA translation, is coupled to meiosis completion at egg activation. Elife 6 PubMed GONUTS page
- ↑ Lee, LA & Orr-Weaver, TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu. Rev. Genet. 37 545-78 PubMed GONUTS page
