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DROME:PLU
Contents
Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
Gene Name(s) | plu | |
Protein Name(s) | DNA replication inhibitor plutonium | |
External Links | ||
UniProt | P42570 | |
EMBL | U03986 AE013599 | |
PIR | S41713 | |
RefSeq | NP_476683.1 | |
ProteinModelPortal | P42570 | |
SMR | P42570 | |
BioGrid | 69325 | |
DIP | DIP-24015N | |
IntAct | P42570 | |
MINT | MINT-769934 | |
PRIDE | P42570 | |
EnsemblMetazoa | FBtr0086306 | |
GeneID | 44848 | |
KEGG | dme:Dmel_CG9183 | |
UCSC | CG9183-RA | |
CTD | 44848 | |
FlyBase | FBgn0003114 | |
eggNOG | NOG240093 | |
InParanoid | P42570 | |
OMA | NYFGQNA | |
OrthoDB | EOG7M3J1N | |
PhylomeDB | P42570 | |
SignaLink | P42570 | |
GenomeRNAi | 44848 | |
NextBio | 837719 | |
Proteomes | UP000000803 | |
Bgee | P42570 | |
ExpressionAtlas | P42570 | |
GO | GO:0006260 GO:0007343 GO:0008156 GO:0007346 GO:0007338 | |
Gene3D | 1.25.40.20 | |
InterPro | IPR002110 IPR020683 | |
Pfam | PF00023 | |
SMART | SM00248 | |
SUPFAM | SSF48403 | |
PROSITE | PS50297 PS50088 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0045977 |
positive regulation of mitotic cell cycle, embryonic |
ECO:0000314 |
P |
See Figure 5B. Co-expressor with PNG. |
complete | |||||
GO:0045977 |
positive regulation of mitotic cell cycle, embryonic |
ECO:0000315 |
P |
See the comparisons of the mutant and wild-type genotypes in figure 7. |
complete | |||||
involved_in |
GO:0007343 |
egg activation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:1902554 |
serine/threonine protein kinase complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0000826 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0008156 |
negative regulation of DNA replication |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007338 |
single fertilization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:1902911 |
protein kinase complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007346 |
regulation of mitotic cell cycle |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006260 |
DNA replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Fenger, DD et al. (2000) PAN GU: a protein kinase that inhibits S phase and promotes mitosis in early Drosophila development. Development 127 4763-74 PubMed GONUTS page
- ↑ Tadros, W et al. (2003) Regulation of maternal transcript destabilization during egg activation in Drosophila. Genetics 164 989-1001 PubMed GONUTS page
- ↑ 3.0 3.1 Axton, JM et al. (1994) The inhibitor of DNA replication encoded by the Drosophila gene plutonium is a small, ankyrin repeat protein. EMBO J. 13 462-70 PubMed GONUTS page
- ↑ Hara, M et al. (2017) Control of PNG kinase, a key regulator of mRNA translation, is coupled to meiosis completion at egg activation. Elife 6 PubMed GONUTS page
- ↑ Lee, LA & Orr-Weaver, TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu. Rev. Genet. 37 545-78 PubMed GONUTS page