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DROME:PERO

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) Pxd (synonyms: HDC14047, PO)
Protein Name(s) Peroxidase

DmPO Chorion peroxidase

External Links
UniProt Q01603
EMBL X68131
AY541497
AE014297
BK002598
PIR S28222
RefSeq NP_001163633.1
NP_996223.1
UniGene Dm.31257
ProteinModelPortal Q01603
SMR Q01603
IntAct Q01603
PeroxiBase 4118
PaxDb Q01603
PRIDE Q01603
EnsemblMetazoa FBtr0089287
FBtr0301526
GeneID 2768671
KEGG dme:Dmel_CG3477
UCSC CG3477-RA
CTD 2768671
FlyBase FBgn0004577
eggNOG NOG271029
GeneTree ENSGT00550000074325
InParanoid Q01603
OMA HPTRCCT
OrthoDB EOG7QK0BF
PhylomeDB Q01603
GenomeRNAi 2768671
NextBio 848013
Proteomes UP000000803
Bgee Q01603
ExpressionAtlas Q01603
GO GO:0042600
GO:0005576
GO:0020037
GO:0046872
GO:0004601
GO:0007306
GO:0042744
GO:0022008
GO:0006909
Gene3D 1.10.640.10
InterPro IPR010255
IPR019791
IPR029585
PANTHER PTHR11475:SF41
Pfam PF03098
PRINTS PR00457
SUPFAM SSF48113
PROSITE PS50292

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0055114

oxidation-reduction process

PMID:24459295[1]

IMP: Inferred from Mutant Phenotype

P

The Mutations observed allow the activity to be found.

complete
CACAO 10603

GO:0004601

peroxidase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010255
InterPro:IPR029585

F

Seeded From UniProt

complete

GO:0004601

peroxidase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:1.11.1.7

F

Seeded From UniProt

complete

GO:0004601

peroxidase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0575

F

Seeded From UniProt

complete

GO:0004601

peroxidase activity

PMID:15979004[2]

ISS: Inferred from Sequence or Structural Similarity

F

Seeded From UniProt

Missing: with/from

GO:0005576

extracellular region

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

GO:0006909

phagocytosis

PMID:16336044[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0006979

response to oxidative stress

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010255

P

Seeded From UniProt

complete

GO:0007306

eggshell chorion assembly

PMID:15979004[2]

NAS: Non-traceable Author Statement

P

Seeded From UniProt

complete

GO:0016491

oxidoreductase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

GO:0020037

heme binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010255

F

Seeded From UniProt

complete

GO:0022008

neurogenesis

PMID:21549331[4]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0042600

chorion

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR029585

C

Seeded From UniProt

complete

GO:0042600

chorion

PMID:15979004[2]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0042744

hydrogen peroxide catabolic process

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0376

P

Seeded From UniProt

complete

GO:0045471

response to ethanol

PMID:25387828[5]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0046872

metal ion binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010255

P

Seeded From UniProt

complete

GO:0055114

oxidation-reduction process

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Angeles, DC et al. (2014) Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila. Hum. Mol. Genet. 23 3157-65 PubMed GONUTS page
  2. 2.0 2.1 2.2 Konstandi, OA et al. (2005) The enzymatic component of Drosophila melanogaster chorion is the Pxd peroxidase. Insect Biochem. Mol. Biol. 35 1043-57 PubMed GONUTS page
  3. Stroschein-Stevenson, SL et al. (2006) Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol. 4 e4 PubMed GONUTS page
  4. Neumüller, RA et al. (2011) Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Cell Stem Cell 8 580-93 PubMed GONUTS page
  5. Logan-Garbisch, T et al. (2014) Developmental ethanol exposure leads to dysregulation of lipid metabolism and oxidative stress in Drosophila. G3 (Bethesda) 5 49-59 PubMed GONUTS page