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DROME:PERO

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) Pxd (synonyms: HDC14047, PO)
Protein Name(s) Peroxidase

DmPO Chorion peroxidase

External Links
UniProt Q01603
EMBL X68131
AY541497
AE014297
BK002598
PIR S28222
RefSeq NP_001163633.1
NP_996223.1
UniGene Dm.31257
ProteinModelPortal Q01603
SMR Q01603
IntAct Q01603
PeroxiBase 4118
PaxDb Q01603
PRIDE Q01603
EnsemblMetazoa FBtr0089287
FBtr0301526
GeneID 2768671
KEGG dme:Dmel_CG3477
UCSC CG3477-RA
CTD 2768671
FlyBase FBgn0004577
eggNOG NOG271029
GeneTree ENSGT00550000074325
InParanoid Q01603
OMA HPTRCCT
OrthoDB EOG7QK0BF
PhylomeDB Q01603
GenomeRNAi 2768671
NextBio 848013
Proteomes UP000000803
Bgee Q01603
ExpressionAtlas Q01603
GO GO:0042600
GO:0005576
GO:0020037
GO:0046872
GO:0004601
GO:0007306
GO:0042744
GO:0022008
GO:0006909
Gene3D 1.10.640.10
InterPro IPR010255
IPR019791
IPR029585
PANTHER PTHR11475:SF41
Pfam PF03098
PRINTS PR00457
SUPFAM SSF48113
PROSITE PS50292

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0055114

oxidation-reduction process

PMID:24459295[1]

ECO:0000315

P

The Mutations observed allow the activity to be found.

complete
CACAO 10603

enables

GO:0004601

peroxidase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107569
MGI:MGI:1923363
MGI:MGI:97137
PANTHER:PTN000158755
RGD:1592081
UniProtKB:P05164
UniProtKB:Q92626
WB:WBGene00009897
WB:WBGene00022743

F

Seeded From UniProt

complete

enables

GO:0004601

peroxidase activity

PMID:15979004[3]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

involved_in

GO:0007306

eggshell chorion assembly

PMID:15979004[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0042600

chorion

PMID:15979004[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0098869

cellular oxidant detoxification

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004601

P

Seeded From UniProt

complete

involved_in

GO:0098869

cellular oxidant detoxification

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004601

P

Seeded From UniProt

complete

involved_in

GO:0098869

cellular oxidant detoxification

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004601

P

Seeded From UniProt

complete

involved_in

GO:0098869

cellular oxidant detoxification

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004601

P

Seeded From UniProt

complete

involved_in

GO:0098869

cellular oxidant detoxification

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004601

P

Seeded From UniProt

complete

enables

GO:0004601

peroxidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010255
InterPro:IPR029585

F

Seeded From UniProt

complete

involved_in

GO:0006979

response to oxidative stress

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010255

P

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010255

F

Seeded From UniProt

complete

part_of

GO:0042600

chorion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029585

C

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010255

P

Seeded From UniProt

complete

enables

GO:0004601

peroxidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.11.1.7

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0042744

hydrogen peroxide catabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0376

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

enables

GO:0004601

peroxidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0575

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Angeles, DC et al. (2014) Thiol peroxidases ameliorate LRRK2 mutant-induced mitochondrial and dopaminergic neuronal degeneration in Drosophila. Hum. Mol. Genet. 23 3157-65 PubMed GONUTS page
  2. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 3.2 Konstandi, OA et al. (2005) The enzymatic component of Drosophila melanogaster chorion is the Pxd peroxidase. Insect Biochem. Mol. Biol. 35 1043-57 PubMed GONUTS page