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DROME:O46308

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided.
Protein Name(s) EG:8D8.5 protein (ECO:0000313 with EMBL:CAA17681.1)

Pan gu (ECO:0000313 with EMBL:AAF45611.1) Protein kinase PAN GU (ECO:0000313 with EMBL:AAG28782.1)

External Links
UniProt O46308
EMBL AE014298
AF306498
AL022018
PIR T13619
RefSeq NP_477492.1
UniGene Dm.3473
SMR O46308
DIP DIP-19818N
MINT MINT-1031982
STRING 7227.FBpp0070225
EnsemblMetazoa FBtr0070234
GeneID 31084
KEGG dme:Dmel_CG11420
UCSC CG11420-RA
CTD 31084
FlyBase FBgn0000826
eggNOG COG0515
GeneTree ENSGT00760000119011
KO K08286
OMA VNIVMEY
OrthoDB EOG7S21ZT
PhylomeDB O46308
GenomeRNAi 31084
NextBio 771856
Proteomes UP000000803
GO GO:0005524
GO:0004674
GO:0007343
GO:0007346
InterPro IPR011009
IPR000719
IPR008271
Pfam PF00069
SUPFAM SSF56112
PROSITE PS50011
PS00108

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0045977

positive regulation of mitotic cell cycle, embryonic

PMID:11044392[1]

ECO:0000315

P

See Figure 3 for comparison to the wild type and png alleles.

complete
CACAO 5077

GO:0016301

kinase activity

PMID:11044392[1]

ECO:0000315

F

See Figure 7 for CDC2 kinase activity.

complete
CACAO 5797

involved_in

GO:0045977

positive regulation of mitotic cell cycle, embryonic

PMID:11044392[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007343

egg activation

PMID:12871909[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:1902554

serine/threonine protein kinase complex

PMID:11044392[1]

ECO:0000353

physical interaction evidence used in manual assertion

FB:FBgn0003114

C

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

PMID:11044392[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

PMID:11044392[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

PMID:28555567[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

PMID:28555567[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:1902911

protein kinase complex

PMID:28555567[3]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:O46308,UniProtKB:P42570

C

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

involved_in

GO:0007346

regulation of mitotic cell cycle

PMID:14616073[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

PMID:14616073[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Fenger, DD et al. (2000) PAN GU: a protein kinase that inhibits S phase and promotes mitosis in early Drosophila development. Development 127 4763-74 PubMed GONUTS page
  2. Tadros, W et al. (2003) Regulation of maternal transcript destabilization during egg activation in Drosophila. Genetics 164 989-1001 PubMed GONUTS page
  3. 3.0 3.1 3.2 Hara, M et al. (2017) Control of PNG kinase, a key regulator of mRNA translation, is coupled to meiosis completion at egg activation. Elife 6 PubMed GONUTS page
  4. 4.0 4.1 Lee, LA & Orr-Weaver, TL (2003) Regulation of cell cycles in Drosophila development: intrinsic and extrinsic cues. Annu. Rev. Genet. 37 545-78 PubMed GONUTS page