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DROME:GMDS

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) Gmd
Protein Name(s) GDP-mannose 4,6 dehydratase

GDP-D-mannose dehydratase Dm-gmd

External Links
UniProt Q9VMW9
EMBL AM231687
AE014134
AY089519
RefSeq NP_608888.2
UniGene Dm.4967
ProteinModelPortal Q9VMW9
SMR Q9VMW9
BioGrid 59900
PaxDb Q9VMW9
EnsemblMetazoa FBtr0079049
GeneID 33716
KEGG dme:Dmel_CG8890
CTD 33716
FlyBase FBgn0031661
eggNOG COG1089
GeneTree ENSGT00440000033640
InParanoid Q9VMW9
KO K01711
OMA TDCLYLG
OrthoDB EOG7K6PV5
PhylomeDB Q9VMW9
UniPathway UPA00128
GenomeRNAi 33716
NextBio 784930
PRO PR:Q9VMW9
Proteomes UP000000803
Bgee Q9VMW9
ExpressionAtlas Q9VMW9
GO GO:0050662
GO:0008446
GO:0042351
GO:0042350
GO:0019673
GO:0007219
GO:0048477
GO:2000035
Gene3D 3.40.50.720
HAMAP MF_00955
InterPro IPR001509
IPR006368
IPR016040
Pfam PF01370
TIGRFAMs TIGR01472

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0007219

Notch signaling pathway

PMID:21965616[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0008446

GDP-mannose 4,6-dehydratase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006368

F

Seeded From UniProt

complete

GO:0008446

GDP-mannose 4,6-dehydratase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:4.2.1.47

F

Seeded From UniProt

complete

GO:0008446

GDP-mannose 4,6-dehydratase activity

PMID:16650000[2]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0016829

lyase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

GO:0019673

GDP-mannose metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006368

P

Seeded From UniProt

complete

GO:0042350

GDP-L-fucose biosynthetic process

PMID:16650000[2]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0042351

'de novo' GDP-L-fucose biosynthetic process

GO_REF:0000041

IEA: Inferred from Electronic Annotation

UniPathway:UPA00128

P

Seeded From UniProt

complete

GO:0048477

oogenesis

PMID:23450845[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:2000035

regulation of stem cell division

PMID:21965616[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Perdigoto, CN et al. (2011) Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestine. Development 138 4585-95 PubMed GONUTS page
  2. 2.0 2.1 Rhomberg, S et al. (2006) Reconstitution in vitro of the GDP-fucose biosynthetic pathways of Caenorhabditis elegans and Drosophila melanogaster. FEBS J. 273 2244-56 PubMed GONUTS page
  3. Jagut, M et al. (2013) A mosaic genetic screen for genes involved in the early steps of Drosophila oogenesis. G3 (Bethesda) 3 409-25 PubMed GONUTS page