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DROME:G9L8C4

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) TrpA1 (ECO:0000313 with EMBL:AEU17952.1)
Protein Name(s) TRPA1(A) isoform (ECO:0000313 with EMBL:AEU17952.1)
External Links
UniProt G9L8C4
EMBL JQ015263
SignaLink G9L8C4
ExpressionAtlas G9L8C4
GO GO:0016021
GO:0005216
Gene3D 1.25.40.20
InterPro IPR002110
IPR020683
IPR005821
IPR030288
PANTHER PTHR24171:SF3
Pfam PF00023
PF12796
PF00520
PRINTS PR01415
SMART SM00248
SUPFAM SSF48403
PROSITE PS50297
PS50088

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0009408

response to heat

PMID:22139422[1]

IMP: Inferred from Mutant Phenotype

P

Figure 4 references mutating either a cysteine (C105) or two basic residues (R113, R116) in TRPA1(A) markedly increased temperature responsiveness (Fig. 4a–c and Supplementary Figs 6 and 7). The temperatures used were from 27–37 degrees C (warming).

complete
CACAO 5312

GO:0005216

ion channel activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821
InterPro:IPR030288

F

Seeded From UniProt

complete

GO:0006810

transport

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

Seeded From UniProt

complete

GO:0006811

ion transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

P

Seeded From UniProt

complete

GO:0006811

ion transport

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

GO:0009408

response to heat

PMID:22139422[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

C

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR030288

C

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

GO:0034220

ion transmembrane transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR030288

P

Seeded From UniProt

complete

GO:0055085

transmembrane transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Kang, K et al. (2012) Modulation of TRPA1 thermal sensitivity enables sensory discrimination in Drosophila. Nature 481 76-80 PubMed GONUTS page