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DROME:CATL
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | Cp1 (synonyms: fs(2)50Ca) | |
| Protein Name(s) | Cathepsin L
Cysteine proteinase 1 Cathepsin L heavy chain Cathepsin L light chain | |
| External Links | ||
| UniProt | Q95029 | |
| EMBL | U75652 AF012089 AE013599 AE013599 BT016071 D31970 | |
| RefSeq | NP_523735.2 NP_725347.1 | |
| UniGene | Dm.7400 | |
| ProteinModelPortal | Q95029 | |
| SMR | Q95029 | |
| BioGrid | 62300 | |
| IntAct | Q95029 | |
| MINT | MINT-814156 | |
| STRING | 7227.FBpp0086719 | |
| MEROPS | C01.092 | |
| PaxDb | Q95029 | |
| PRIDE | Q95029 | |
| EnsemblMetazoa | FBtr0087593 | |
| GeneID | 36546 | |
| KEGG | dme:Dmel_CG6692 | |
| CTD | 36546 | |
| FlyBase | FBgn0013770 | |
| eggNOG | COG4870 | |
| GeneTree | ENSGT00760000118871 | |
| InParanoid | Q95029 | |
| KO | K01365 | |
| OMA | ACTSLAR | |
| OrthoDB | EOG786H3P | |
| PhylomeDB | Q95029 | |
| Reactome | REACT_180993 REACT_184283 REACT_215998 REACT_235465 REACT_247955 REACT_257704 REACT_268980 | |
| GenomeRNAi | 36546 | |
| NextBio | 799136 | |
| PRO | PR:Q95029 | |
| Proteomes | UP000000803 | |
| Bgee | Q95029 | |
| ExpressionAtlas | Q95029 | |
| GO | GO:0045169 GO:0005764 GO:0004197 GO:0048102 GO:0007586 GO:0006508 GO:0035071 | |
| InterPro | IPR025661 IPR000169 IPR025660 IPR013128 IPR000668 IPR013201 | |
| PANTHER | PTHR12411 | |
| Pfam | PF08246 PF00112 | |
| PRINTS | PR00705 | |
| SMART | SM00848 SM00645 | |
| PROSITE | PS00640 PS00139 PS00639 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0051603 |
proteolysis involved in cellular protein catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:107341 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005764 |
lysosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0013770 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0034229 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004197 |
cysteine-type endopeptidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0013770 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005764 |
lysosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004197 |
cysteine-type endopeptidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045169 |
fusome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008234 |
cysteine-type peptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008234 |
cysteine-type peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007586 |
digestion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005764 |
lysosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Kowalewski-Nimmerfall, E et al. (2014) Drosophila melanogaster cellular repressor of E1A-stimulated genes is a lysosomal protein essential for fly development. Biochim. Biophys. Acta 1843 2900-12 PubMed GONUTS page
- ↑ 3.0 3.1 Tseng, TS et al. (2012) A molten globule-to-ordered structure transition of Drosophila melanogaster crammer is required for its ability to inhibit cathepsin. Biochem. J. 442 563-72 PubMed GONUTS page
- ↑ Lighthouse, DV et al. (2008) New components of the Drosophila fusome suggest it plays novel roles in signaling and transport. Dev. Biol. 317 59-71 PubMed GONUTS page
