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DICDI:CFAD

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Species (Taxon ID) Dictyostelium discoideum (Slime mold). (44689)
Gene Name(s) cfaD
Protein Name(s) Counting factor associated protein D
External Links
UniProt Q54TR1
EMBL AAFI02000042
RefSeq XP_640530.1
ProteinModelPortal Q54TR1
SMR Q54TR1
STRING 44689.DDB0229857
MEROPS C01.067
PaxDb Q54TR1
EnsemblProtists EAL66564
GeneID 8623140
KEGG ddi:DDB_G0281605
dictyBase DDB_G0281605
eggNOG KOG1543
COG4870
InParanoid Q54TR1
OMA PSEDYNG
PhylomeDB Q54TR1
Reactome R-DDI-2132295
R-DDI-5683826
R-DDI-6798695
PRO PR:Q54TR1
Proteomes UP000002195
UP000002195
GO GO:0031410
GO:0005576
GO:0005615
GO:0005764
GO:1903665
GO:1903669
GO:0072659
GO:0031288
GO:0030435
InterPro IPR000169
IPR025660
IPR013128
IPR000668
IPR013201
PANTHER PTHR12411
Pfam PF08246
PF00112
PRINTS PR00705
SMART SM00848
SM00645
PROSITE PS00139
PS00639

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0072659

protein localization to plasma membrane

PMID:23555023[1]

ECO:0000314

direct assay evidence used in manual assertion

P

has_participant:(UniProtKB:Q54JL7)

Seeded From UniProt

complete

involved_in

GO:1903669

positive regulation of chemorepellent activity

PMID:22711818[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030435

sporulation resulting in formation of a cellular spore

PMID:18611962[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

NOT|acts_upstream_of_or_within

GO:0019954

asexual reproduction

PMID:18611962[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

PMID:18611962[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0031288

sorocarp morphogenesis

PMID:18611962[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1903665

negative regulation of asexual reproduction

PMID:21760904[4]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:Q54LU5

P

Seeded From UniProt

complete

involved_in

GO:1903665

negative regulation of asexual reproduction

PMID:18611962[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

NOT|enables

GO:0008234

cysteine-type peptidase activity

PMID:18611962[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

NOT|involved_in

GO:0006508

proteolysis

PMID:18611962[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

PMID:18611962[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0051603

proteolysis involved in cellular protein catabolic process

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:107341
PANTHER:PTN000274640
UniProtKB:P07711
UniProtKB:P07858
UniProtKB:P25774
UniProtKB:P43235

P

Seeded From UniProt

complete

part_of

GO:0005764

lysosome

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0013770
MGI:MGI:107341
MGI:MGI:1860262
MGI:MGI:88561
MGI:MGI:88564
PANTHER:PTN000274640
RGD:2445
RGD:2447
RGD:2448
RGD:61810
RGD:621509
UniProtKB:P07711
UniProtKB:P07858
UniProtKB:P09668
UniProtKB:P25774
UniProtKB:Q9UBR2
WB:WBGene00000786
dictyBase:DDB_G0279187

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0034229
FB:FBgn0034709
MGI:MGI:88564
PANTHER:PTN000274640
RGD:2447
RGD:61810
RGD:621509
RGD:708479
UniProtKB:P07711
UniProtKB:P07858
UniProtKB:P09668
UniProtKB:P25774
UniProtKB:P43235
UniProtKB:Q9UBR2

C

Seeded From UniProt

complete

enables

GO:0004197

cysteine-type endopeptidase activity

PMID:21873635[5]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0013770
FB:FBgn0030521
MGI:MGI:107285
MGI:MGI:107341
PANTHER:PTN000274640
RGD:2448
RGD:621509
TAIR:locus:2133402
TAIR:locus:2157712
TAIR:locus:2204873
TAIR:locus:505006093
UniProtKB:P07711
UniProtKB:P07858
UniProtKB:P09668
UniProtKB:P25774
UniProtKB:P43235
UniProtKB:Q8IIL0

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Herlihy, SE et al. (2013) A Dictyostelium secreted factor requires a PTEN-like phosphatase to slow proliferation and induce chemorepulsion. PLoS ONE 8 e59365 PubMed GONUTS page
  2. Phillips, JE & Gomer, RH (2012) A secreted protein is an endogenous chemorepellant in Dictyostelium discoideum. Proc. Natl. Acad. Sci. U.S.A. 109 10990-5 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Bakthavatsalam, D et al. (2008) The secreted Dictyostelium protein CfaD is a chalone. J. Cell. Sci. 121 2473-80 PubMed GONUTS page
  4. Phillips, JE et al. (2011) The putative bZIP transcription factor BzpN slows proliferation and functions in the regulation of cell density by autocrine signals in Dictyostelium. PLoS ONE 6 e21765 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page