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DANRE:Q9W767
Contents
| Species (Taxon ID) | Danio rerio (Zebrafish) (Brachydanio rerio). (7955) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Midkine-related growth factor (ECO:0000313 with EMBL:AAH71342.1)
Midkine-related growth factor Mdk1 (ECO:0000313 with EMBL:AAM27446.1) Pleiotrophin 1 (ECO:0000313 with EMBL:AAD38157.1) Uncharacterized protein (ECO:0000313 with Ensembl:ENSDARP00000052317) | |
| External Links | ||
| UniProt | Q9W767 | |
| EMBL | CR356225 AF149802 BC071342 AF503614 | |
| RefSeq | NP_571145.1 | |
| UniGene | Dr.31448 | |
| PDB | 2LUT | |
| PDBsum | 2LUT | |
| STRING | 7955.ENSDARP00000052317 | |
| Ensembl | ENSDART00000052318 ENSDART00000124343 | |
| GeneID | 30277 | |
| KEGG | dre:30277 | |
| CTD | 30277 | |
| ZFIN | ZDB-GENE-990621-1 | |
| eggNOG | NOG39111 | |
| GeneTree | ENSGT00390000007640 | |
| HOGENOM | HOG000231473 | |
| HOVERGEN | HBG008317 | |
| KO | K06828 | |
| OMA | NAQCQET | |
| TreeFam | TF332376 | |
| Reactome | REACT_233416 | |
| NextBio | 20806723 | |
| Proteomes | UP000000437 | |
| GO | GO:0001841 GO:0051726 | |
| Gene3D | 2.20.60.10 2.30.90.10 | |
| InterPro | IPR000762 IPR020090 IPR020091 IPR020089 | |
| PANTHER | PTHR13850 | |
| Pfam | PF01091 PF05196 | |
| PRINTS | PR00269 | |
| ProDom | PD005592 | |
| SMART | SM00193 | |
| SUPFAM | SSF57288 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005829 |
cytosol |
ECO:0000314 |
C |
" These experiments show co-localization of the GFP and Mdka immunofluorescence, demonstrating that in horizontal cells the Mdka immunolabel is cytosolic (Fig. 2A). " |
complete | |||||
| GO:0005737 |
cytoplasm |
ECO:0000314 |
C |
"As seen in Figure 2, immunolabels for both Mdka and EGFP colocalize to the cytoplasm of horizontal cells (arrowhead, panel A). " |
complete | |||||
| GO:0005794 |
Golgi apparatus |
ECO:0000314 |
C |
As seen in Figure 2, "In the adult retina, Mdka immunostaining colocalizes with the antibody marker of the Golgi complex (column B; and insets)" |
complete | |||||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070654 |
sensory epithelium regeneration |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-050531-5 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051726 |
regulation of cell cycle |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-050531-5 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051726 |
regulation of cell cycle |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-GENO-130416-1 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001841 |
neural tube formation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-050531-5 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008083 |
growth factor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000354681 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0008083 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008083 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008083 |
growth factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000762 |
F |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Gramage, E et al. (2015) Midkine-a protein localization in the developing and adult retina of the zebrafish and its function during photoreceptor regeneration. PLoS ONE 10 e0121789 PubMed GONUTS page
- ↑ 2.0 2.1 Luo, J et al. (2012) Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina. Neural Dev 7 33 PubMed GONUTS page
- ↑ Schäfer, M et al. (2005) Medial floor plate formation in zebrafish consists of two phases and requires trunk-derived Midkine-a. Genes Dev. 19 897-902 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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