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DANRE:Q5RHJ3

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) No Information Provided.
Protein Name(s) Uncharacterized protein (ECO:0000313 with Ensembl:ENSDARP00000025716)
External Links
UniProt Q5RHJ3
EMBL BX296520
BX324141
BX511069
RefSeq NP_001025307.1
XP_005160559.1
XP_005160560.1
UniGene Dr.74015
SMR Q5RHJ3
Ensembl ENSDART00000004984
ENSDART00000152290
GeneID 560060
KEGG dre:560060
CTD 560060
ZFIN ZDB-GENE-030131-4212
GeneTree ENSGT00760000118986
HOGENOM HOG000237318
HOVERGEN HBG101333
KO K04512
OMA QNSAMAP
OrthoDB EOG7B8S37
PhylomeDB Q5RHJ3
TreeFam TF314602
Reactome REACT_202432
NextBio 20883270
Proteomes UP000000437
GO GO:0030036
GO:0060026
InterPro IPR016024
IPR027650
IPR014767
IPR015425
IPR010472
IPR010473
IPR014768
PANTHER PTHR23213:SF181
Pfam PF06367
PF06371
PF02181
SMART SM00498
SUPFAM SSF48371
PROSITE PS51231
PS51444
PS51232

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0060026

convergent extension

PMID:17412835[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010472
InterPro:IPR010473

F

Seeded From UniProt

complete

GO:0030139

endocytic vesicle

PMID:17412835[1]

ECO:0000314

C

Fig. 1A shows the localization of Daam1 to the endocytic vesicles.

complete

involved_in

GO:0016043

cellular component organization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010472

P

Seeded From UniProt

complete

enables

GO:0017048

Rho GTPase binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010473

F

Seeded From UniProt

complete

GO:0048570

notochord morphogenesis

PMID:17412835[1]

ECO:0000315

P

Figure 9A shows that when Daam1 is blocked, the tail is short and bent tail and cyclopia, related to the morphogenesis of the notochord. Morpholino oligonucleotide was used to inactivate the Daam1 resulting in the mutant phenotype.

complete

involved_in

GO:0030036

actin cytoskeleton organization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010473

P

Seeded From UniProt

complete

GO:0030863

cortical cytoskeleton

PMID:17412835[1]

ECO:0000314

C

Figure 4D shows that Daam1 colocalizes with the cytoskeleton at the cell cortex identified through fluorescence. This is further stated in the paragraph on page 6711 with the heading of cytoskeleton and Daam1.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Kida, YS et al. (2007) Daam1 regulates the endocytosis of EphB during the convergent extension of the zebrafish notochord. Proc. Natl. Acad. Sci. U.S.A. 104 6708-13 PubMed GONUTS page