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DANRE:Q50J87
Contents
| Species (Taxon ID) | Danio rerio (Zebrafish) (Brachydanio rerio). (7955) | |
| Gene Name(s) | prnpb (ECO:0000313 with ZFIN:ZDB-GENE-041221-2) | |
| Protein Name(s) | PrP1 protein (ECO:0000313 with EMBL:CAG28804.1) | |
| External Links | ||
| UniProt | Q50J87 | |
| EMBL | AJ704630 | |
| UniGene | Dr.90045 | |
| ProteinModelPortal | Q50J87 | |
| PRIDE | Q50J87 | |
| ZFIN | ZDB-GENE-041221-2 | |
| HOVERGEN | HBG056090 | |
| GO | GO:0016020 GO:0051260 | |
| Gene3D | 1.10.790.10 | |
| InterPro | IPR022416 | |
| SUPFAM | SSF54098 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0007156 |
homophilic cell adhesion |
ECO:0000315 |
P |
Fig 9 |
complete | |||||
|
involved_in |
GO:0007156 |
homophilic cell adhesion via plasma membrane adhesion molecules |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:2000047 |
regulation of cell-cell adhesion mediated by cadherin |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-100423-5 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:2000047 |
regulation of cell-cell adhesion mediated by cadherin |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-100423-4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0061097 |
regulation of protein tyrosine kinase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-100423-4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055113 |
epiboly involved in gastrulation with mouth forming second |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-050421-1 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055113 |
epiboly involved in gastrulation with mouth forming second |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-100423-5 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055113 |
epiboly involved in gastrulation with mouth forming second |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-100423-4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0034334 |
adherens junction maintenance |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-100423-4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016338 |
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-100423-5 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016338 |
calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-100423-4 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0009986 |
cell surface |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007417 |
central nervous system development |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-100423-4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007156 |
homophilic cell adhesion via plasma membrane adhesion molecules |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003674 |
molecular_function |
ECO:0000307 |
no biological data found used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051260 |
protein homooligomerization |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Málaga-Trillo, E et al. (2009) Regulation of embryonic cell adhesion by the prion protein. PLoS Biol. 7 e55 PubMed GONUTS page
- ↑ 2.0 2.1 Sempou, E et al. (2016) Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo. Mol Neurodegener 11 18 PubMed GONUTS page
- ↑ Miesbauer, M et al. (2006) Prion protein-related proteins from zebrafish are complex glycosylated and contain a glycosylphosphatidylinositol anchor. Biochem. Biophys. Res. Commun. 341 218-24 PubMed GONUTS page
- ↑ Kaiser, DM et al. (2012) Amyloid beta precursor protein and prion protein have a conserved interaction affecting cell adhesion and CNS development. PLoS ONE 7 e51305 PubMed GONUTS page
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