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DANRE:Q32SK8

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) ntn4 (ECO:0000313 with ZFIN:ZDB-GENE-050310-1)
Protein Name(s) Netrin 4 (ECO:0000313 with EMBL:AAY17260.1)
External Links
UniProt Q32SK8
EMBL AY928519
RefSeq NP_001032775.1
UniGene Dr.84045
ProteinModelPortal Q32SK8
GeneID 561440
KEGG dre:561440
CTD 59277
ZFIN ZDB-GENE-050310-1
HOVERGEN HBG082019
KO K06845
NextBio 20883930
GO GO:0005576
InterPro IPR002049
IPR008211
IPR001134
IPR018933
IPR008993
Pfam PF00053
PF00055
PF01759
SMART SM00180
SM00136
SUPFAM SSF50242
PROSITE PS01248
PS50027
PS51117
PS50189

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001944

vasculature development

PMID:22179604[1]

IMP: Inferred from Mutant Phenotype

P

Table 2 shows that Netrin-4 down-regulation in zebrafish leads to blood vessel formation defects and the authors additionally noted that only blood vessel formation was altered, not blood circulation, heartbeat or somite formation.

complete
CACAO 4691

GO:0001944

vasculature development

PMID:22179604[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0005576

extracellular region

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Lambert, E et al. (2012) Netrin-4 acts as a pro-angiogenic factor during zebrafish development. J. Biol. Chem. 287 3987-99 PubMed GONUTS page