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DANRE:Q288P2
Contents
Species (Taxon ID) | Danio rerio (Zebrafish) (Brachydanio rerio). (7955) | |
Gene Name(s) | bmpr2b (ECO:0000313 with ZFIN:ZDB-GENE-070618-2) | |
Protein Name(s) | BMP type IIb receptor (ECO:0000313 with EMBL:AAY45945.1) | |
External Links | ||
UniProt | Q288P2 | |
EMBL | DQ002899 | |
RefSeq | NP_001034896.1 | |
UniGene | Dr.134746 | |
ProteinModelPortal | Q288P2 | |
SMR | Q288P2 | |
GeneID | 555655 | |
KEGG | dre:555655 | |
CTD | 555655 | |
ZFIN | ZDB-GENE-070618-2 | |
HOGENOM | HOG000043088 | |
HOVERGEN | HBG050705 | |
KO | K04671 | |
PhylomeDB | Q288P2 | |
NextBio | 20881097 | |
GO | GO:0016021 GO:0005524 GO:0004702 GO:0005024 GO:0030509 GO:0007368 GO:0003146 GO:0001947 GO:0048570 | |
InterPro | IPR000472 IPR015770 IPR011009 IPR000719 IPR017441 IPR000333 | |
PANTHER | PTHR23255 PTHR23255:SF63 | |
Pfam | PF01064 PF00069 | |
SUPFAM | SSF56112 | |
PROSITE | PS00107 PS50011 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0048570 |
notochord morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030509 |
BMP signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007368 |
determination of left/right symmetry |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-080722-6 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007368 |
determination of left/right symmetry |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007368 |
determination of left/right symmetry |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-080722-8 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0005024 |
transforming growth factor beta-activated receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0003146 |
heart jogging |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-080722-8 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0003146 |
heart jogging |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-080722-7 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0002040 |
sprouting angiogenesis |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ZFIN:ZDB-GENE-070618-1 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0002040 |
sprouting angiogenesis |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ZFIN:ZDB-GENE-030131-7745 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0002040 |
sprouting angiogenesis |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ZFIN:ZDB-GENE-030131-1571 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001947 |
heart looping |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-080722-8 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001947 |
heart looping |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-080722-7 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001945 |
lymph vessel development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-110729-3 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0098821 |
BMP receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1095407 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0046332 |
SMAD binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98728 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0043235 |
receptor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000583675 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0019838 |
growth factor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:102806 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007389 |
pattern specification process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1338938 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007179 |
transforming growth factor beta receptor signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003716 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:87911 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005026 |
transforming growth factor beta receptor activity, type II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001147423 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0005024 |
transforming growth factor beta-activated receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98728 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004672 |
protein kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004675 |
transmembrane receptor protein serine/threonine kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007178 |
transmembrane receptor protein serine/threonine kinase signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016301 |
kinase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Monteiro, R et al. (2008) Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish. Dev. Biol. 315 55-71 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Wakayama, Y et al. (2015) Cdc42 mediates Bmp-induced sprouting angiogenesis through Fmnl3-driven assembly of endothelial filopodia in zebrafish. Dev. Cell 32 109-22 PubMed GONUTS page
- ↑ Kim, JD & Kim, J (2014) Alk3/Alk3b and Smad5 mediate BMP signaling during lymphatic development in zebrafish. Mol. Cells 37 270-4 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
c
p
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- Teleostei
- GO:0016740 ! transferase activity
- GO:0007179 ! transforming growth factor beta receptor signaling pathway
- GO:0005026 ! transforming growth factor beta receptor activity, type II
- GO:0005024 ! transforming growth factor beta receptor activity
- GO:0004675 ! transmembrane receptor protein serine/threonine kinase activity