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DANRE:Q288P2

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) bmpr2b (ECO:0000313 with ZFIN:ZDB-GENE-070618-2)
Protein Name(s) BMP type IIb receptor (ECO:0000313 with EMBL:AAY45945.1)
External Links
UniProt Q288P2
EMBL DQ002899
RefSeq NP_001034896.1
UniGene Dr.134746
ProteinModelPortal Q288P2
SMR Q288P2
GeneID 555655
KEGG dre:555655
CTD 555655
ZFIN ZDB-GENE-070618-2
HOGENOM HOG000043088
HOVERGEN HBG050705
KO K04671
PhylomeDB Q288P2
NextBio 20881097
GO GO:0016021
GO:0005524
GO:0004702
GO:0005024
GO:0030509
GO:0007368
GO:0003146
GO:0001947
GO:0048570
InterPro IPR000472
IPR015770
IPR011009
IPR000719
IPR017441
IPR000333
PANTHER PTHR23255
PTHR23255:SF63
Pfam PF01064
PF00069
SUPFAM SSF56112
PROSITE PS00107
PS50011

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

GO:0001945

lymph vessel development

PMID:24608800[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110729-3

P

Seeded From UniProt

complete

GO:0001947

heart looping

PMID:18222420[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-080722-7

P

Seeded From UniProt

complete

GO:0001947

heart looping

PMID:18222420[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-080722-8

P

Seeded From UniProt

complete

GO:0003146

heart jogging

PMID:18222420[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-080722-7

P

Seeded From UniProt

complete

GO:0003146

heart jogging

PMID:18222420[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-080722-8

P

Seeded From UniProt

complete

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

Seeded From UniProt

complete

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

Seeded From UniProt

complete

GO:0004675

transmembrane receptor protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000472

F

Seeded From UniProt

complete

GO:0004702

receptor signaling protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000333

F

Seeded From UniProt

complete

GO:0005024

transforming growth factor beta-activated receptor activity

PMID:18222420[2]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000333
InterPro:IPR000719
InterPro:IPR017441

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

P

Seeded From UniProt

complete

GO:0007178

transmembrane receptor protein serine/threonine kinase signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000333

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:18222420[2]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-MRPHLNO-080722-6
ZFIN:ZDB-MRPHLNO-080722-8

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:18222420[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:18222420[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-080722-8

P

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000333
InterPro:IPR000472

C

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

GO:0016301

kinase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

GO:0016310

phosphorylation

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

GO:0016740

transferase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

GO:0023014

signal transduction by protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000333

P

Seeded From UniProt

complete

GO:0030509

BMP signaling pathway

PMID:18222420[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0048570

notochord morphogenesis

PMID:18222420[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Kim, JD & Kim, J (2014) Alk3/Alk3b and Smad5 mediate BMP signaling during lymphatic development in zebrafish. Mol. Cells 37 270-4 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 2.9 Monteiro, R et al. (2008) Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish. Dev. Biol. 315 55-71 PubMed GONUTS page