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DANRE:NKD1

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) nkd1
Protein Name(s) Protein naked cuticle homolog 1

Naked-1

External Links
UniProt Q2TJA6
EMBL AY863053
RefSeq NP_001036798.1
UniGene Dr.135817
Ensembl ENSDART00000052379
GeneID 751108
KEGG dre:751108
CTD 85407
ZFIN ZDB-GENE-061108-3
eggNOG NOG47986
GeneTree ENSGT00440000033589
HOGENOM HOG000005649
HOVERGEN HBG099718
InParanoid Q2TJA6
KO K03213
OMA EEFECGV
OrthoDB EOG75F4D6
PhylomeDB Q2TJA6
TreeFam TF328786
NextBio 20917761
PRO PR:Q2TJA6
Proteomes UP000000437
Bgee Q2TJA6
GO GO:0005737
GO:0005886
GO:0005509
GO:0060971
GO:0001754
GO:0003146
GO:0070121
GO:0060972
GO:0090090
GO:0035414
GO:0001839
GO:0090249
GO:0007525
GO:0060061
GO:0016055
Gene3D 1.10.238.10
InterPro IPR011992
IPR018247
IPR002048
PROSITE PS00018
PS50222

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001754

eye photoreceptor cell differentiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSXETP00000039973

P

Seeded From UniProt

complete

GO:0001839

neural plate morphogenesis

PMID:17689523[1]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENO-071130-2
ZFIN:ZDB-MRPHLNO-071203-3

P

Seeded From UniProt

complete

GO:0003146

heart jogging

PMID:20858476[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-101209-4

P

Seeded From UniProt

complete

GO:0005509

calcium ion binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002048

F

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

PMID:21490931[3]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

GO:0005886

plasma membrane

PMID:21490931[3]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0007525

somatic muscle development

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSXETP00000039973

P

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

GO:0016055

Wnt signaling pathway

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0879

P

Seeded From UniProt

complete

GO:0016055

Wnt signaling pathway

PMID:17689523[1]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-980526-332

P

Seeded From UniProt

complete

GO:0016055

Wnt signaling pathway

PMID:17689523[1]

IGI: Inferred from Genetic Interaction

ZFIN:ZDB-GENE-990603-12

P

Seeded From UniProt

complete

GO:0016055

Wnt signaling pathway

PMID:17689523[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-071130-1

P

Seeded From UniProt

complete

GO:0016055

Wnt signaling pathway

PMID:17689523[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-228

P

Seeded From UniProt

complete

GO:0035414

negative regulation of catenin import into nucleus

PMID:21490931[3]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0046872

metal ion binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

GO:0060061

Spemann organizer formation

PMID:17689523[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-071203-3

P

Seeded From UniProt

complete

GO:0060971

embryonic heart tube left/right pattern formation

PMID:20858476[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-101209-4

P

Seeded From UniProt

complete

GO:0060972

left/right pattern formation

PMID:20858476[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-101209-4

P

Seeded From UniProt

complete

GO:0070121

Kupffer's vesicle development

PMID:20858476[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-101209-4

P

Seeded From UniProt

complete

GO:0090090

negative regulation of canonical Wnt signaling pathway

PMID:21490931[3]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0090249

regulation of cell motility involved in somitogenic axis elongation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSXETP00000039973

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Van Raay, TJ et al. (2007) Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signaling. Dev. Biol. 309 151-68 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Schneider, I et al. (2010) Zebrafish Nkd1 promotes Dvl degradation and is required for left-right patterning. Dev. Biol. 348 22-33 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Van Raay, TJ et al. (2011) Naked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-catenin. PLoS ONE 6 e18650 PubMed GONUTS page