GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
DANRE:F1QC45
Contents
| Species (Taxon ID) | Danio rerio (Zebrafish) (Brachydanio rerio). (7955) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Uncharacterized protein (ECO:0000313 with Ensembl:ENSDARP00000120363) | |
| External Links | ||
| UniProt | F1QC45 | |
| EMBL | BX322552 | |
| RefSeq | XP_005166034.1 XP_005166035.1 | |
| UniGene | Dr.161717 Dr.80773 | |
| Ensembl | ENSDART00000136920 | |
| GeneID | 406755 | |
| KEGG | dre:406755 | |
| CTD | 6102 | |
| ZFIN | ZDB-GENE-040426-2795 | |
| GeneTree | ENSGT00530000063741 | |
| InParanoid | F1QC45 | |
| KO | K18272 | |
| OMA | QWYYPEL | |
| OrthoDB | EOG7ZPNKQ | |
| TreeFam | TF105832 | |
| PRO | PR:F1QC45 | |
| Proteomes | UP000000437 | |
| Bgee | F1QC45 | |
| GO | GO:0005524 GO:0004550 GO:0000902 GO:0006241 GO:0007010 GO:0006183 GO:0001947 GO:0042461 GO:0035845 GO:0048793 GO:0060041 GO:0010842 GO:0006228 | |
| Gene3D | 2.160.20.70 | |
| InterPro | IPR013912 IPR017901 IPR016098 IPR006599 IPR001564 IPR017332 IPR012945 | |
| PANTHER | PTHR15440:SF0 | |
| Pfam | PF00334 PF07986 | |
| PIRSF | PIRSF037947 | |
| SMART | SM00673 | |
| SUPFAM | SSF54919 SSF69340 | |
| PROSITE | PS51329 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0061371 |
determination of heart left/right asymmetry |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-101122-1 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0060041 |
retina development in camera-type eye |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-120222-8 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0048793 |
pronephros development |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-060630-4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0048793 |
pronephros development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-101122-2 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045494 |
photoreceptor cell maintenance |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-GENO-170615-12 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042461 |
photoreceptor cell development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-110725-3 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035845 |
photoreceptor cell outer segment organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-110725-3 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010842 |
retina layer formation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-120222-8 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001947 |
heart looping |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-101122-1 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001947 |
heart looping |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
ZFIN:ZDB-MRPHLNO-101122-2 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043547 |
positive regulation of GTPase activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005096 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043547 |
positive regulation of GTPase activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005096 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000902 |
cell morphogenesis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005096 |
GTPase activator activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015031 |
protein transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005525 |
GTP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005096 |
GTPase activator activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042995 |
cell projection |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005929 |
cilium |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Desvignes, T et al. (2015) X-Linked Retinitis Pigmentosa 2 Is a Novel Maternal-Effect Gene Required for Left-Right Asymmetry in Zebrafish. Biol. Reprod. 93 42 PubMed GONUTS page
- ↑ 2.0 2.1 Shu, X et al. (2011) Knockdown of the zebrafish ortholog of the retinitis pigmentosa 2 (RP2) gene results in retinal degeneration. Invest. Ophthalmol. Vis. Sci. 52 2960-6 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Hurd, T et al. (2010) The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development. Hum. Mol. Genet. 19 4330-44 PubMed GONUTS page
- ↑ Liu, F et al. (2017) Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish. J. Biol. Chem. 292 6225-6239 PubMed GONUTS page
- ↑ 5.0 5.1 Patil, SB et al. (2011) Functional analysis of retinitis pigmentosa 2 (RP2) protein reveals variable pathogenic potential of disease-associated missense variants. PLoS ONE 6 e21379 PubMed GONUTS page
c
p
