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DANRE:E9QIK2

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) No Information Provided.
Protein Name(s) Uncharacterized protein (ECO:0000313 with Ensembl:ENSDARP00000117120)
External Links
UniProt E9QIK2
EMBL CR356225
PRIDE E9QIK2
Ensembl ENSDART00000146635
ZFIN ZDB-GENE-990621-1
GeneTree ENSGT00390000007640
OrthoDB EOG7B05G6
Reactome REACT_233416
Proteomes UP000000437
Bgee E9QIK2
Gene3D 2.20.60.10
2.30.90.10
InterPro IPR000762
IPR020090
IPR020091
IPR020089
PANTHER PTHR13850
Pfam PF01091
PF05196
PRINTS PR00269
ProDom PD005592
SMART SM00193
SUPFAM SSF57288

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0051726

regulation of cell cycle

PMID:23111152[1]

ECO:0000315

P

Figure 3(A)(c) shows that in the absence of Mdka, "central retinal progenitors fail to exit the cell cycle at the appropriate developmental stage," implying that "Mdka functions to control cell cycle kinetics."

complete
CACAO 5682

involved_in

GO:0051726

regulation of cell cycle

PMID:23111152[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0070654

sensory epithelium regeneration

PMID:25803551[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-050531-5

P

Seeded From UniProt

complete

involved_in

GO:0051726

regulation of cell cycle

PMID:23111152[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-050531-5

P

Seeded From UniProt

complete

involved_in

GO:0051726

regulation of cell cycle

PMID:23111152[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-GENO-130416-1

P

Seeded From UniProt

complete

involved_in

GO:0001841

neural tube formation

PMID:15833916[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-050531-5

P

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000354681
RGD:3444
UniProtKB:P21246
UniProtKB:P32760
ZFIN:ZDB-GENE-030624-1

F

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008083

P

Seeded From UniProt

complete

enables

GO:0008083

growth factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000762
InterPro:IPR020089
InterPro:IPR020090
InterPro:IPR020091
InterPro:IPR037122

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Luo, J et al. (2012) Midkine-A functions upstream of Id2a to regulate cell cycle kinetics in the developing vertebrate retina. Neural Dev 7 33 PubMed GONUTS page
  2. Gramage, E et al. (2015) Midkine-a protein localization in the developing and adult retina of the zebrafish and its function during photoreceptor regeneration. PLoS ONE 10 e0121789 PubMed GONUTS page
  3. Schäfer, M et al. (2005) Medial floor plate formation in zebrafish consists of two phases and requires trunk-derived Midkine-a. Genes Dev. 19 897-902 PubMed GONUTS page
  4. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page