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DANRE:D2XMV0

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) ptk7b (ECO:0000313 with ZFIN:ZDB-GENE-101124-3)
Protein Name(s) Protein tyrosine kinase 7 long isoform (ECO:0000313 with EMBL:ADB22375.1)
External Links
UniProt D2XMV0
EMBL GU211905
UniGene Dr.158881
ProteinModelPortal D2XMV0
ZFIN ZDB-GENE-101124-3
PhylomeDB D2XMV0
GO GO:0016301
GO:0060026
Gene3D 2.60.40.10
InterPro IPR007110
IPR013783
IPR013098
IPR003599
IPR003598
Pfam PF07679
SMART SM00409
SM00408
PROSITE PS50835

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0048598

embryonic morphogenesis

PMID:23533179[1]

ECO:0000314

P

Figure 2

complete
CACAO 7316

involved_in

GO:0048598

embryonic morphogenesis

PMID:23533179[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0060026

convergent extension

PMID:20837484[2]

ECO:0000316

genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-081029-4
ZFIN:ZDB-MRPHLNO-081029-5
ZFIN:ZDB-MRPHLNO-101124-1

P

Seeded From UniProt

complete

involved_in

GO:0060026

convergent extension

PMID:20837484[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-101124-1

P

Seeded From UniProt

complete

involved_in

GO:0060071

Wnt signaling pathway, planar cell polarity pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:1904929

P

Seeded From UniProt

complete

involved_in

GO:0001736

establishment of planar polarity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033592

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033592

C

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033592

P

Seeded From UniProt

complete

involved_in

GO:0060026

convergent extension

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033592

P

Seeded From UniProt

complete

enables

GO:1904929

coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033592

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Hayes, M et al. (2013) Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/β-catenin-dependent cell fate decisions during vertebrate development. Development 140 1807-18 PubMed GONUTS page
  2. 2.0 2.1 Golubkov, VS et al. (2010) The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis. J. Biol. Chem. 285 35740-9 PubMed GONUTS page