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DANRE:CCD40

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) ccdc40 (synonyms: lok)
Protein Name(s) Coiled-coil domain-containing protein 40

Protein locke

External Links
UniProt Q56A40
EMBL BX005286
CR854963
BC092181
RefSeq NP_001258742.1
UniGene Dr.157455
Dr.25001
Ensembl ENSDART00000002617
ENSDART00000145154
GeneID 568590
KEGG dre:568590
CTD 55036
ZFIN ZDB-GENE-060503-723
eggNOG NOG138528
GeneTree ENSGT00440000035688
HOGENOM HOG000111411
InParanoid Q56A40
OMA TTQAEGQ
OrthoDB EOG747PHC
PhylomeDB Q56A40
TreeFam TF325559
Proteomes UP000000437
Bgee Q56A40
GO GO:0005929
GO:0005737
GO:0070286
GO:0035082
GO:0042384
GO:0003341
GO:0007368
GO:0003143
GO:0003351
GO:0060287
GO:0003146
GO:0001947
GO:0048793
InterPro IPR013956
Pfam PF08647

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001947

heart looping

PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0003143

embryonic heart tube morphogenesis

PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0003146

heart jogging

PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0003341

cilium movement

PMID:21131974[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0003341

cilium movement

PMID:21131974[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110125-2

P

Seeded From UniProt

complete

GO:0003341

cilium movement

PMID:21131974[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110125-3

P

Seeded From UniProt

complete

GO:0003351

epithelial cilium movement

PMID:17576052[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0003674

molecular_function

GO_REF:0000015

ND: No biological Data available

F

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q8BI79

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

GO:0005737

cytoplasm

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

GO:0005929

cilium

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q8BI79

C

Seeded From UniProt

complete

GO:0005929

cilium

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0969

C

Seeded From UniProt

complete

GO:0005929

cilium

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0066

C

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:17576052[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:21131974[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:21131974[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110125-2

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:21131974[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110125-3

P

Seeded From UniProt

complete

GO:0007368

determination of left/right symmetry

PMID:9334285[1]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0035082

axoneme assembly

PMID:17576052[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0035082

axoneme assembly

PMID:21131974[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0042384

cilium assembly

PMID:17576052[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0042384

cilium assembly

PMID:21131974[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110125-2

P

Seeded From UniProt

complete

GO:0042384

cilium assembly

PMID:21131974[2]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-MRPHLNO-110125-3

P

Seeded From UniProt

complete

GO:0042995

cell projection

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

GO:0048793

pronephros development

PMID:17576052[3]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0048793

pronephros development

PMID:9007249[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-105

P

Seeded From UniProt

complete

GO:0048793

pronephros development

PMID:9007249[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1297

P

Seeded From UniProt

complete

GO:0048793

pronephros development

PMID:9007249[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-1298

P

Seeded From UniProt

complete

GO:0048793

pronephros development

PMID:9007249[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-543

P

Seeded From UniProt

complete

GO:0048793

pronephros development

PMID:9007249[4]

IMP: Inferred from Mutant Phenotype

ZFIN:ZDB-GENO-980202-956

P

Seeded From UniProt

complete

GO:0060287

epithelial cilium movement involved in determination of left/right asymmetry

PMID:21131974[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0070286

axonemal dynein complex assembly

GO_REF:0000024

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q4G0X9

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Chen, JN et al. (1997) Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development 124 4373-82 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 2.9 Becker-Heck, A et al. (2011) The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation. Nat. Genet. 43 79-84 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Zhao, C & Malicki, J (2007) Genetic defects of pronephric cilia in zebrafish. Mech. Dev. 124 605-16 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Chen, JN et al. (1996) Mutations affecting the cardiovascular system and other internal organs in zebrafish. Development 123 293-302 PubMed GONUTS page