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DANRE:CAPR2

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) caprin2 (ECO:0000312 with EMBL:AAH57503.1) (synonyms: rng140)
Protein Name(s) Caprin-2

RNA granule protein 140

External Links
UniProt Q5RJ80
EMBL BX001012
BC057503
RefSeq NP_001013291.1
UniGene Dr.81341
PDB 4OUS
PDBsum 4OUS
ProteinModelPortal Q5RJ80
Ensembl ENSDART00000040708
GeneID 407729
KEGG dre:407729
CTD 65981
ZFIN ZDB-GENE-040812-2
eggNOG NOG41180
GeneTree ENSGT00760000119052
HOGENOM HOG000082543
HOVERGEN HBG057777
InParanoid Q5RJ80
OMA NSRAGWS
OrthoDB EOG74XS5W
PhylomeDB Q5RJ80
TreeFam TF329471
NextBio 20818583
PRO PR:Q5RJ80
Proteomes UP000000437
Bgee Q5RJ80
GO GO:0005737
GO:0003723
GO:0009953
GO:0017148
GO:0090263
GO:0050775
GO:0061003
GO:0030177
GO:2000055
GO:0040008
Gene3D 2.60.120.40
InterPro IPR001073
IPR028816
IPR008983
PANTHER PTHR22922
Pfam PF00386
PRINTS PR00007
SMART SM00110
SUPFAM SSF49842
PROSITE PS50871

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009953

dorsal/ventral pattern formation

PMID:18762581[1]

ECO:0000315

P

Figure 3B: Embryos injected with caprin-2beta catenin MO showed dorsalized phenotypes.

complete

GO:0090263

positive regulation of canonical Wnt receptor signaling pathway

PMID:18762581[1]

ECO:0000315

P

Figure 4C: Caprin-2 activates canonical Wnt signalling in zebrafish embryos.

complete

involved_in

GO:2000055

positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification

PMID:18762581[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0090263

positive regulation of canonical Wnt signaling pathway

PMID:18762581[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0061003

positive regulation of dendritic spine morphogenesis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q05A80

P

Seeded From UniProt

complete

involved_in

GO:0050775

positive regulation of dendrite morphogenesis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q05A80

P

Seeded From UniProt

complete

involved_in

GO:0030177

positive regulation of Wnt signaling pathway

PMID:18762581[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-090103-2

P

Seeded From UniProt

complete

involved_in

GO:0030177

positive regulation of Wnt signaling pathway

PMID:18762581[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-090103-1

P

Seeded From UniProt

complete

involved_in

GO:0009953

dorsal/ventral pattern formation

PMID:18762581[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-090103-2

P

Seeded From UniProt

complete

involved_in

GO:0009953

dorsal/ventral pattern formation

PMID:18762581[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-090103-1

P

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0652

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0040008

regulation of growth

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0341

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Ding, Y et al. (2008) Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation. J. Cell Biol. 182 865-72 PubMed GONUTS page