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DANRE:ADA

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Species (Taxon ID) Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s) ada
Protein Name(s) Adenosine deaminase

Adenosine aminohydrolase

External Links
UniProt Q6DG22
EMBL BC076532
RefSeq NP_001002646.1
UniGene Dr.88169
ProteinModelPortal Q6DG22
SMR Q6DG22
STRING 7955.ENSDARP00000005284
GeneID 436919
KEGG dre:436919
CTD 100
ZFIN ZDB-GENE-040718-393
eggNOG COG1816
HOGENOM HOG000218816
HOVERGEN HBG001718
InParanoid Q6DG22
KO K01488
PhylomeDB Q6DG22
NextBio 20831346
PRO PR:Q6DG22
Proteomes UP000000437
GO GO:0030054
GO:0060205
GO:0005886
GO:0004000
GO:0008270
GO:0006154
GO:0046103
GO:0009117
GO:0009168
HAMAP MF_00540
InterPro IPR006650
IPR001365
IPR028893
IPR006330
Pfam PF00962
TIGRFAMs TIGR01430
PROSITE PS00485

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004000

adenosine deaminase activity

PMID:18582589[1]

ECO:0000314

F

Table 2

complete
CACAO 3707

enables

GO:0004000

adenosine deaminase activity

PMID:18582589[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0046103

inosine biosynthetic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P03958

P

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P03958

F

Seeded From UniProt

complete

involved_in

GO:0006154

adenosine catabolic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P03958

P

Seeded From UniProt

complete

enables

GO:0004000

adenosine deaminase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P03958

F

Seeded From UniProt

complete

involved_in

GO:0046103

inosine biosynthetic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:87916
PANTHER:PTN000150817
UniProtKB:P00813

P

Seeded From UniProt

complete

involved_in

GO:0043103

hypoxanthine salvage

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10030
PANTHER:PTN000150817

P

Seeded From UniProt

complete

involved_in

GO:0006154

adenosine catabolic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10030
FB:FBgn0033952
FB:FBgn0036752
FB:FBgn0038172
MGI:MGI:87916
PANTHER:PTN000150817
UniProtKB:P00813
UniProtKB:Q9NZK5

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10030
PANTHER:PTN000150817
UniProtKB:P00813

C

Seeded From UniProt

complete

enables

GO:0004000

adenosine deaminase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10030
FB:FBgn0033952
FB:FBgn0036752
FB:FBgn0038172
MGI:MGI:87916
PANTHER:PTN000150817
RGD:2031
UniProtKB:P00813
UniProtKB:Q6DHV7
UniProtKB:Q8IJA9
UniProtKB:Q9NZK5

F

Seeded From UniProt

complete

enables

GO:0004000

adenosine deaminase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR028893

F

Seeded From UniProt

complete

involved_in

GO:0009168

purine ribonucleoside monophosphate biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006650
InterPro:IPR028893

P

Seeded From UniProt

complete

enables

GO:0019239

deaminase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001365
InterPro:IPR006330
InterPro:IPR006650

F

Seeded From UniProt

complete

enables

GO:0004000

adenosine deaminase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.5.4.4

F

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0968

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

involved_in

GO:0009117

nucleotide metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0546

P

Seeded From UniProt

complete

part_of

GO:0005764

lysosome

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0458
UniProtKB-SubCell:SL-0158

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965
UniProtKB-SubCell:SL-0038

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0060205

cytoplasmic vesicle lumen

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0325

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Rosemberg, DB et al. (2008) Kinetic characterization of adenosine deaminase activity in zebrafish (Danio rerio) brain. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 151 96-101 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page