DANRE:A9YT50

Species (Taxon ID)	Danio rerio (Zebrafish) (Brachydanio rerio). (7955)
Gene Name(s)	No Information Provided. (synonyms: pkr (ECO:0000313 with EMBL:CAM07150.1))
Protein Name(s)	Double-stranded RNA activated protein kinase (ECO:0000313 with EMBL:CAM07150.1) IFN-stimulated dsRNA-activated eIF2-alpha kinase 2 (ECO:0000313 with EMBL:ABY47905.1)
External Links
UniProt	A9YT50
EMBL	EU289209 AM421526
RefSeq	NP_001107942.1
UniGene	Dr.143197
STRING	7955.ENSDARP00000090291
GeneID	100001092
KEGG	dre:100001092
CTD	5610
ZFIN	ZDB-GENE-080422-1
eggNOG	COG0515
HOGENOM	HOG000206018
HOVERGEN	HBG066915
KO	K16195
NextBio	20784899
GO	GO:0005524 GO:0004674
Gene3D	3.30.160.20
InterPro	IPR014720 IPR011009 IPR000719 IPR017441 IPR008271
Pfam	PF00035 PF00069
SMART	SM00358
SUPFAM	SSF56112
PROSITE	PS50137 PS00107 PS50011 PS00108

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0004672	protein kinase activity	PMID:18312693	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0022626	cytosolic ribosome		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000867953 SGD:S000002691	C		Seeded From UniProt	complete
enables	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1341830 MGI:MGI:1353427 PANTHER:PTN000867953 PomBase:SPBC36B7.09 RGD:70884 SGD:S000002691 UniProtKB:A0A0B4KHX7 UniProtKB:A0A1D8PQT9 UniProtKB:P19525 UniProtKB:Q9NZJ5 UniProtKB:Q9P2K8 dictyBase:DDB_G0272837	F		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103075 MGI:MGI:1341830 MGI:MGI:1353448 MGI:MGI:1353449 PANTHER:PTN000113601 PomBase:SPBC36B7.09 SGD:S000002691 TAIR:locus:2024780 UniProtKB:P19525 UniProtKB:Q8IL26 WB:WBGene00006988 ZFIN:ZDB-GENE-050301-2 ZFIN:ZDB-GENE-080422-1	F		Seeded From UniProt	complete
enables	GO:0003725	double-stranded RNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033366	F		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271	F		Seeded From UniProt	complete
enables	GO:0004674	protein serine/threonine kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033366	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR017441	F		Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR008271	P		Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033366	P		Seeded From UniProt	complete
involved_in	GO:0009615	response to virus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033366	P		Seeded From UniProt	complete
involved_in	GO:0009636	response to toxic substance	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033366	P		Seeded From UniProt	complete
involved_in	GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033366	P		Seeded From UniProt	complete
involved_in	GO:0042981	regulation of apoptotic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033366	P		Seeded From UniProt	complete
involved_in	GO:0045071	negative regulation of viral genome replication	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033366	P		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000415048	F		Seeded From UniProt	complete
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References

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