Category:GO:1990628 ! obsolete Sigma-E factor negative regulation complex

This GO term has been obsoleted. Do not annotate to it.

id: GO:1990628
name: obsolete Sigma-E factor negative regulation complex
namespace: cellular_component
def: "OBSOLETE. A protein complex consisting of RseA, RseB and RpoE. It form the inactive form of the sigma-E transcription factor. In response to stress, outer membrane proteins accumulate in the periplasm and activate cleavage of RseA periplasmic domain by DegS, triggering a proteolytic cascade that frees sigma-E to activate gene expression. RseB binding to RseA prevents activated DegS from cleaving RseA. Sigma-E-mediated envelope stress response is the major pathway to ensure homeostasis in the envelope compartment of the cell." [GOC:bhm, PMID:20190044]
comment: This term was obsoleted at the TermGenie Gatekeeper stage.
synonym: "RseA-RseB-RpoE complex" RELATED []
synonym: "Sigma-E factor negative regulation complex" EXACT []
is_obsolete: true

AmiGO <GOterm>GO:1990628</GOterm>
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