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Category:GO:1990455 ! PTEN phosphatase complex
name: PTEN phosphatase complex
namespace: cellular_component
def: "A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function." [GOC:bhm, PMID:24766807]
comment: An example of this is PTEN in human (P60484) in PMID:24766807 (inferred from direct assay).
synonym: "phosphatase and tensin homolog" EXACT []
synonym: "phosphatase and tensin homolog deleted on chromosome ten homodimer" EXACT []
synonym: "phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN homodimer" EXACT []
is_a: GO:1904144 ! phosphatidylinositol phosphate phosphatase complex
AmiGO
<GOterm>GO:1990455</GOterm>
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