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Category:GO:0160005 ! PAT complex
name: PAT complex
namespace: cellular_component
def: "A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the correct folding of multipass membrane proteins in the ER membrane. In human, the substrate-binding Asterix (PAT10, WDR83OS) forms an obligate heterodimer with CCDC47." [PMID:32814900, PMID:33082068, PMID:33960686]
comment: PAT complex functions by shielding exposed hydrophilicity of transmembrane domains (TMDs) to prevent premature degradation and promote proper folding and bundling of TMDs.
is_a: GO:0098796 ! membrane protein complex
is_a: GO:0140534 ! endoplasmic reticulum protein-containing complex
relationship: part_of: GO:0005789 ! endoplasmic reticulum membrane
AmiGO
<GOterm>GO:0160005</GOterm>
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