GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Category:GO:0141133 ! diphthine methyl ester synthase activity
name: diphthine methyl ester synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 3 H+ + 4 S-adenosyl-L-homocysteine." [PMID:24739148, RHEA:42652]
comment: This activity is present in eukaryotes and is part of the biosynthetic pathway of diphthamide. Note that this is different from the archaeal enzyme, diphthine synthase activity ; GO:0004164 (EC:2.1.1.98), which performs only 3 methylations, producing diphthine.
xref: EC:2.1.1.314
xref: MetaCyc:RXN-15775
xref: RHEA:42652
is_a: GO:0008276 ! protein methyltransferase activity
is_a: GO:0008757 ! S-adenosylmethionine-dependent methyltransferase activity
AmiGO
<GOterm>GO:0141133</GOterm>
Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Usage Notes
References
See Help:References for how to manage references in GONUTS.
This category currently contains no pages or media.
