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Category:GO:0141040 ! very-long-chain 3-oxoacyl-CoA reductase activity
name: very-long-chain 3-oxoacyl-CoA reductase activity
namespace: molecular_function
def: "Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ = a very-long-chain 3-oxoacyl-CoA + H+ + NADPH. This reaction is the second (reduction) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit." [PMID:16564093, PMID:19763486, RHEA:48680]
xref: EC:1.1.1.330
xref: MetaCyc:RXN-7698
xref: RHEA:48680
is_a: GO:0016616 ! oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
AmiGO
<GOterm>GO:0141040</GOterm>
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