name: BCOR complex
The contents of this box are automatically generated. You can help by adding information to the "Notes"
def: "A protein-containing complex that monoubiquitinates histone H2A on K119, thus it facilitates the maintenance of the transcriptionally repressive state of some genes, such as BCL6. It consists of the corepressor BCOR or BCORL1, a Polycomb group (PcG) and a SCF ubiquitin ligase subcomplexes. In mammals, the core subunits of the complex include the PcG and PcG-associated proteins NSPC1, RING1, RNF2, and RYBP and the components of the SCF ubiquitin ligase, SKP1, and FBXL10." [PMID:16943429, PMID:22325352, PMID:24515802]
synonym: "BCL6 corepressor (BCOR) complex" EXACT 
synonym: "BCOR/BCORL1 complex" EXACT 
synonym: "non-canonical BCOR-PRC1.1 complex" EXACT 
synonym: "non-canonical PRC1-BCOR complex" EXACT 
synonym: "PRC1.1 complex" EXACT 
is_a: GO:0000152 ! nuclear ubiquitin ligase complex
Gene Ontology Home
See Help:References for how to manage references in GONUTS.
This category currently contains no pages or media.