Category:GO:0140036 ! ubiquitin-modified protein reader activity

name: ubiquitin-modified protein reader activity
namespace: molecular_function
def: "A molecular adaptor recognizes and binds a target protein containing a ubiquitination modification and brings the target protein into contact with another protein to allow those proteins to function in a coordinated way." [PMID:26060076]
comment: This term should only be used when the binding is shown to require ubiquitination of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of ubiquitination. It may be that the ubiquitination causes a conformational change that allows binding of the protein to another region; this type of ubiquitination-dependent protein binding is valid for annotation to this term.
synonym: "ubiquitin-dependent protein binding" EXACT []
is_a: GO:0140035 ! ubiquitin-like protein reader activity

AmiGO <GOterm>GO:0140036</GOterm>
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