Category:GO:0106151 ! CNBH domain intrinsic ligand binding

name: CNBH domain intrinsic ligand binding
namespace: molecular_function
def: "Interacting selectivity and noncovalently with a cyclic nucleotide mimicking protein motif that is part of the same protein. The CNBHD is a domain on KCNH channels that creates a binding pocket on the KCNH channel that resembles the cyclic nucleotide- binding domain on other ion channels. It binds to a peptide motif that is part of the same protein rather than a cyclic nucleotide." [GOC:cvs, PMID:27025590, PMID:29567795]
comment: It is unclear if the motif bound by CNBHD is a specific motif or just a beta sheet with the appropriate amino acids.
is_a: GO:0005515 ! protein binding

AmiGO <GOterm>GO:0106151</GOterm>
Gene Ontology Home