Category:GO:0097655 ! serpin family protein binding

name: serpin family protein binding
namespace: molecular_function
def: "Binding to a member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors." [GOC:mr, InterPro:IPR000215, PMID:16737556]
is_a: GO:0005515 ! protein binding

AmiGO <GOterm>GO:0097655</GOterm>
Gene Ontology Home