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Category:GO:0097597 ! ventral disc
name: ventral disc
namespace: cellular_component
def: "Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved in adherence." [GOC:giardia, ISBN:9780124260207, PMID:11432808, PMID:4777416, PMID:5961344]
comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
synonym: "adhesive disc" RELATED []
synonym: "ventral adhesive disc" EXACT []
synonym: "ventral disk" RELATED []
is_a: GO:0043232 ! intracellular membraneless organelle
relationship: has_part: GO:0097591 ! ventral disc lateral crest
relationship: has_part: GO:0097592 ! ventral disc overlap zone
relationship: has_part: GO:0097594 ! ventral disc dorsal microribbon
relationship: has_part: GO:0097595 ! ventral disc crossbridge
AmiGO
<GOterm>GO:0097597</GOterm>
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This category has the following 6 subcategories, out of 6 total.
