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Category:GO:0097361 ! cytosolic (4Fe-4S) assembly targeting complex
name: cytosolic [4Fe-4S] assembly targeting complex
namespace: cellular_component
def: "A protein complex capable of condensing two 2Fe-2S clusters into one 4Fe-4S center in the cytoplasm and nucleus. In humans it consists of MMS19, CIAO1, CIAO2A/CIAO2B, CIAO3. MMS19, CIAO1 and CIAO2A/CIAO2B form a tight 'core' complex, whereas CIAO3 is an 'external' component of this complex." [PMID:23585563, PMID:23891004, PMID:34660592]
synonym: "CIA complex" BROAD []
synonym: "CIA targeting complex" EXACT [PMID:34660592]
synonym: "cytosolic iron-sulfur protein assembly complex" RELATED []
is_a: GO:0140535 ! intracellular protein-containing complex
is_a: GO:1990229 ! iron-sulfur cluster assembly complex
AmiGO
<GOterm>GO:0097361</GOterm>
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