Category:GO:0072546 ! EMC complex

name: EMC complex
namespace: cellular_component
def: "A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the insertion of newly synthesized proteins in the membrane of the ER. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6." [PMID:29242231, PMID:30415835, PMID:32459176]
comment: Note that this complex used to be thought to be involved in ER-mitochondrial membrane tethering, which is required to facilitate lipid transfer from the ER to the mitochondrial membrane, but newer findings show that this was incorrect.
synonym: "endoplasmic reticulum membrane protein complex" BROAD []
synonym: "ER membrane protein complex" BROAD [GOC:mah]
is_a: GO:0098796 ! membrane protein complex
is_a: GO:0140534 ! endoplasmic reticulum protein-containing complex
relationship: part_of: GO:0005789 ! endoplasmic reticulum membrane

AmiGO <GOterm>GO:0072546</GOterm>
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