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Category:GO:0071754 ! IgM immunoglobulin complex, circulating
name: IgM immunoglobulin complex, circulating
namespace: cellular_component
def: "A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:20176268]
comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
synonym: "IgM antibody" EXACT [GOC:add]
is_a: GO:0042571 ! immunoglobulin complex, circulating
is_a: GO:0071753 ! IgM immunoglobulin complex
AmiGO
<GOterm>GO:0071754</GOterm>
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